Actively Recruiting
Early Use of Intra-Aortic Balloon Pump to Unload Left Ventricle During VA-ECMO for Severe Cardiogenic Shock
Led by Assistance Publique - Hôpitaux de Paris · Updated on 2026-04-13
298
Participants Needed
12
Research Sites
4 weeks
Total Duration
AI-Summary
What this Trial Is About
Researchers are evaluating the impact of early preventive left ventricle unloading using an intra-aortic balloon pump IABP in patients receiving venoarterial extracorporeal membrane oxygenation VA-ECMO for severe cardiogenic shock. Cardiogenic shock often results from conditions like acute myocardial infarction or end-stage heart failure, and VA-ECMO is used to support heart function. However, VA-ECMO can increase left ventricular afterload, potentially worsening outcomes by causing complications such as pulmonary congestion and delaying heart recovery or transplantation. Previous studies have produced mixed results, highlighting the need for a well-powered trial to assess early unloading benefits compared to conventional care.
CONDITIONS
Brief Title
Early Preventive Left Ventricle Unloading After VA-ECMO for Refractory Cardiogenic Shock
Research Team
A
Alain COMBES, MD
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