Actively Recruiting
Early Pulmonary Dysfunction in Childhood Cancer Patients
Led by University Children's Hospital Basel · Updated on 2026-05-08
140
Participants Needed
5
Research Sites
1565 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This longitudinal, prospective, multicentre study is to monitor lung function prospectively in childhood cancer patients after diagnosis. The impact of cancer treatment on pulmonary dysfunction non-invasively using lung function, lung imaging and breath analysis as well as clinical symptoms using a questionnaire will be assessed at different time points.
CONDITIONS
Official Title
Early Pulmonary Dysfunction in Childhood Cancer Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participant has had at least one of the following cancer treatments: chest radiation, any chemotherapy, hematopoietic stem cell transplantation (HSCT), or thoracic surgery
- Consent given for registration in the Childhood Cancer Registry (ChCR)
You will not qualify if you...
- No signed informed consent
- Only cancer treatment was surgery outside the chest area
- Relapsed cancer (patients who relapse during the study remain eligible)
- For MRI and lung function tests: participant has respiratory insufficiency with less than 92% oxygen saturation or is on oxygen therapy
- Participant is pregnant
- MRI measurement not possible without sedation
- Presence of metal in the body such as a pacemaker
AI-Screening
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Trial Site Locations
Total: 5 locations
1
University Children's Hospital Basel (UKBB)
Basel, Switzerland, 4056
Actively Recruiting
2
Universitätsklinik für Kinderheilkunde
Bern, Switzerland, 3010
Actively Recruiting
3
Geneva University Hospital
Geneva, Switzerland, 1211
Actively Recruiting
4
Centre hospitalier universitaire vaudois Lausanne
Lausanne, Switzerland, 1011
Actively Recruiting
5
Universitäts-Kinderspital Zürich
Zurich, Switzerland, 8032
Actively Recruiting
Research Team
J
Jakob Usemann, PD Dr. med.
CONTACT
C
Christine Schneider
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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