Actively Recruiting
Early-stage Detection of LIver, Biliary TRAct and PancReatic Cancers
Led by Second Affiliated Hospital, School of Medicine, Zhejiang University · Updated on 2025-02-10
1608
Participants Needed
1
Research Sites
113 weeks
Total Duration
On this page
Sponsors
S
Second Affiliated Hospital, School of Medicine, Zhejiang University
Lead Sponsor
G
Guangzhou Burning Rock Dx Co., Ltd.
Collaborating Sponsor
AI-Summary
What this Trial Is About
LIBRARY is a prospective, multi-center, observational study aimed at detecting early liver, biliary tract, and pancreatic cancers by combining assays of cell-free DNA (cfDNA) methylation, serum protein, and microRNA.
CONDITIONS
Official Title
Early-stage Detection of LIver, Biliary TRAct and PancReatic Cancers
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 40 to 75 years at the time of consenting to the study
- Able to provide written informed consent
- Pathologically confirmed liver, biliary tract, or pancreatic cancer with no prior or ongoing anti-cancer therapy before study blood draw (Cancer Arm)
- Confirmed diagnosis of benign liver, biliary tract, or pancreatic diseases with no prior radical treatment before blood draw (Benign Arm)
- Able to provide sufficient and qualified blood samples (Healthy Arm)
- No cancer-related symptoms within 30 days prior to study screening (Healthy Arm)
- Cancer history with completed curative treatment over 3 years without recurrence (Healthy Arm)
You will not qualify if you...
- Pregnant or lactating women
- Recipients of organ transplant or prior non-autologous bone marrow or stem cell transplant
- Received blood transfusion within 7 days prior to study blood draw (Cancer and Benign Arms)
- Received any anti-cancer therapy within 30 days prior to study blood draw due to diseases other than cancers (Cancer and Benign Arms)
- Have other known malignant tumors or multiple primary tumors (Cancer Arm)
- Confirmed diagnosis of malignancies or precancerous lesions or history of malignant tumors (Benign Arm)
- Insufficient qualified blood samples for study tests (Healthy Arm)
- Received blood transfusion within 30 days prior to study blood draw (Healthy Arm)
- Received anti-infectious therapy within 14 days prior to study blood draw (Healthy Arm)
- Received or undergoing curative cancer treatment within 3 years prior to screening (Healthy Arm)
- Have autoimmune or other diseases with severe comorbidities (Healthy Arm)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
The Second Affiliated Hospital, Zhejiang University School of Medicine
Hangzhou, Zhejiang, China, 310009
Actively Recruiting
Research Team
Y
Yuan Ding, Phd
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
3
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