Actively Recruiting

Age: 1Day - 99Years
All Genders
Healthy Volunteers
ID03481829

Early Tracking of Childhood Health Determinants Study

Led by National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) · Updated on 2026-05-12

1500

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are studying how various factors during pregnancy and early childhood affect the growth and development of children from birth through adulthood. This research focuses on American Indian/Alaska Native and Hispanic pregnant women and their children, examining how maternal health, lifestyle, and environment impact risks like obesity, diabetes, and fatty liver. The study aims to understand connections between maternal conditions and child health outcomes over time. Pregnant women will have three visits during pregnancy, and mothers and children will have multiple visits throughout early childhood up to age 18. Mothers may provide samples like blood, stool, breastmilk, urine, cord blood, and placenta, and both mothers and children will undergo physical exams, ultrasounds, and possibly use activity monitors. Medical records will also be reviewed to gather comprehensive health data. Participants will be followed closely with scheduled visits during pregnancy and at specific intervals through the child's development, including frequent visits in the first two years and annual visits thereafter until age 18. Researchers will measure outcomes such as infant and child BMI, biochemical markers, stool microbiome, and neurocognitive development. The study involves questionnaires, physical exams, sample collections, and ongoing health monitoring for both mother and child over many years.

CONDITIONS

Brief Title

Early Tracking of Childhood Health Determinants (ETCHED) Study

Who Can Participate

Age: 1Day - 99Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Pregnant women aged 18 years or older with pregnancy confirmed by test or ultrasound
  • Self-identify as American Indian or Hispanic
  • Agree to participate with both mother and child for at least 3 years after delivery
  • Mothers carrying multiple fetuses and their live newborns are eligible
  • Mothers can participate with consecutive pregnancies
Not Eligible

You will not qualify if you...

  • Women who are incarcerated or unable to consent
  • Women whose fetus is not viable or who do not plan to continue the pregnancy

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Diagnostic Evaluation

Duration - During pregnancy

Participants undergo initial assessments of maternal risk factors and baseline measurements during pregnancy.

Multiple visits during pregnancy

Long-term Monitoring

Duration - Up to 18 years

Participants' children are monitored for growth, body composition, and neurodevelopment from birth through adolescence.

Visits at birth, 6 weeks, 4, 6, 12, 18, and 24 months, then annually from age 2 to 18 years

Trial Site Locations

Total: 1 location

1

NIDDK, Phoenix

Phoenix, Arizona, United States, 85014

Actively Recruiting

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Research Team

M

Madhumita Sinha, M.D.

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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Published Research Related To This Trial

Study protocol for Early Tracking of Childhood Health determinants (ETCHED): A longitudinal observational life course study.

Elsa Vazquez Arreola, Dean V Coonrod, Sourav Roy Choudhury...

https://pubmed.ncbi.nlm.nih.gov/39343891