Actively Recruiting

Phase 3
Age: 18Years - 65Years
All Genders
NCT04910464

Early Tranexamic Acid and Modulating the Inflammatory Response in Sepsis

Led by Assiut University · Updated on 2025-08-05

80

Participants Needed

1

Research Sites

295 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

In this study, our aim is to investigate the role tranexamic acid in modulating inflammation in patients with sepsis.

CONDITIONS

Official Title

Early Tranexamic Acid and Modulating the Inflammatory Response in Sepsis

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 to 65 years
  • American Society of Anesthesiologists (ASA) class I-II
  • Diagnosed with sepsis with a qSOFA score of 2 or higher
  • Require ICU admission
Not Eligible

You will not qualify if you...

  • Chronic renal failure
  • Liver cirrhosis
  • Bleeding disorders or current anticoagulant therapy
  • Pregnancy or breastfeeding
  • Impaired color vision
  • Severe vascular ischemia, history of venous thrombosis or pulmonary embolism
  • Long-term treatment with acetylsalicylic acid or NSAIDs not stopped before ICU admission
  • Allergy to tranexamic acid (TXA)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Assiut university hospital

Asyut, Egypt

Actively Recruiting

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Research Team

O

Omar Soliman

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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