Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT04208126

Early Versus Late Initiation of ECMO (Extracorporal Membrane Oxygenation) Trial (ELIEO-Trial)

Led by University Hospital Tuebingen · Updated on 2025-05-23

508

Participants Needed

1

Research Sites

195 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This trial is a prospective randomized multicenter trial that assigns patients to either a treatment for Acute Respiratory Distress Syndrome (ARDS) with an Extracorporal Membrane Oxygenation (ECMO) immediately after admission to the intensive care unit or conservative treatment. The later can undergo ECMO following failure of conservative therapy as a rescue therapy. Patients will be included within 24 hours of the onset of symptoms of ARDS and will be randomized according to standard procedure. Follow-up will be performed until day 90 after study inclusion.

CONDITIONS

Official Title

Early Versus Late Initiation of ECMO (Extracorporal Membrane Oxygenation) Trial (ELIEO-Trial)

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • ARDS as defined by the Berlin Definition
  • Acute onset with hypoxemia and chest radiograph criteria lasting 7 days or less at randomization
  • Enrollment within 96 hours of ARDS onset
  • Enrollment no later than 7 days after starting mechanical ventilation
Not Eligible

You will not qualify if you...

  • Age under 18 years
  • More than 7 days since starting mechanical ventilation
  • More than 96 hours since meeting ARDS inclusion criteria
  • Lack of commitment to full intensive care support by patient, surrogate, or physician
  • Pregnancy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University hospital Tübingen

Tübingen, Germany, 72076

Actively Recruiting

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Research Team

P

Peter Rosenberger, Prof.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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