Actively Recruiting

Phase Not Applicable
Age: 18Years - 90Years
All Genders
NCT05108844

Early Videocapsule Endoscopy for Upper Gastrointestinal Bleeding

Led by University of Alberta · Updated on 2026-03-16

70

Participants Needed

1

Research Sites

273 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The objective of this study is to determine whether early video capsule endoscopy (VCE) immediately after a negative gastroscopy in the setting of suspected upper gastrointestinal bleeding (UGIB) improves patient outcomes as compared to the standard approach which typically involves performing colonoscopy prior to small bowel investigations. We aim to examine the differences in diagnostic yield, total number of procedures, length of hospitalization, mortality rates, and healthcare cost between the two groups.

CONDITIONS

Official Title

Early Videocapsule Endoscopy for Upper Gastrointestinal Bleeding

Who Can Participate

Age: 18Years - 90Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • New onset of acute gastrointestinal bleeding shown by melena or maroon stool within 48 hours of emergency room visit
  • Hemoglobin drop of 20 g/L or more from patient's baseline
  • Ability to provide informed consent
  • Hemodynamically stable at time of consent (blood pressure > 100/60 and pulse < 110)
  • Initial gastroscopy shows no active bleeding or potential bleeding source
Not Eligible

You will not qualify if you...

  • Unable to provide consent due to lack of capacity, language barrier, or other reasons
  • Pregnant women
  • History of small bowel surgery
  • History of Crohn's disease
  • History of small bowel or colonic strictures
  • History of abdominal radiation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Alberta Hospital

Edmonton, Alberta, Canada

Actively Recruiting

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Research Team

S

Sergio Zepeda-Gomez, MD

CONTACT

D

David Yang, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

2

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