Actively Recruiting

Age: 2Days - 36Months
All Genders
ID05865093

Early Visual Functions in Patients at Risk of Developing Cerebral Visual Impairment. A Pilot Study

Led by Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Updated on 2023-05-18

700

Participants Needed

1

Research Sites

195 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are studying early visual function in infants who may develop cerebral visual impairment due to brain or eye-related problems. The study focuses on babies from neonatal age up to 36 months old who are at risk because of conditions like brain lesions or ocular diseases. This pilot study aims to better understand how vision develops in these young patients over time. The study observes infants without testing any treatments or interventions. Researchers will assess visual abilities and correlate these findings with brain MRI results to understand the relationship between brain structure and vision function. Participants will be followed and evaluated regularly over a period of five years to track their visual development and neurological status. During the study, infants will undergo visual function assessments and brain imaging evaluations. The researchers will collect data on visual performance scores and compare them with MRI results to better understand visual impairment risks. The total participation includes assessments up to 36 months of age, with long-term follow-up planned for five years to monitor outcomes and correlations between visual function and brain health.

CONDITIONS

Brief Title

Early Visual Functions in Patients at Risk of Developing Cerebral Visual Impairment. A Pilot Study

Who Can Participate

Age: 2Days - 36Months
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 34 weeks of post-menstrual age and 36 months of life in children born before 37 weeks gestational age
  • Diagnosis of genetic syndromes
  • Diagnosis of hypoxic ischemic encephalopathy
  • Presence of brain malformations
  • Diagnosis of metabolic diseases
  • Presence of ocular pathologies
Not Eligible

You will not qualify if you...

  • Patients at low risk of developing neurological outcomes
  • Refusal of informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Long-term Monitoring

Duration - Up to 5 years

Participants are observed over time to assess early visual functions and correlate functional visual assessment with MRI scores.

Regular visits over 5 years

Trial Site Locations

Total: 1 location

1

Fondazione Policlinico Gemelli

Rome, Italy, 00168

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Research Team

D

Daniela Ricci, Medical Doctor

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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