Telehealth Randomized Trial of EASE Writing Therapy to Reduce Fear and Trauma Symptoms in Adults with Advanced Cancer

What this Trial Is About

This research focuses on adults with advanced solid tumor cancers who often experience significant fear of cancer progression FoP and related trauma symptoms. The study evaluates a novel behavioral intervention called EASE, based on written exposure therapy, aimed at reducing these fears and trauma symptoms. This trial is the first known randomized study in the United States to assess such an intervention delivered via telehealth, addressing gaps in supportive care for advanced cancer patients. Participants receive either the EASE intervention, which includes six individual telehealth sessions of structured writing focused on their cancer-related fears and coping strategies, or usual care involving access to supportive care providers like social workers and nurse practitioners. The sessions last about 60 minutes each and include identifying worst-case scenarios, engaging in exposure writing, and coping writing. Usual care participants continue with standard supportive services available at their treatment sites. Throughout the study, participants complete assessments before, during, and after the intervention, including fear of progression questionnaires and measures of trauma symptoms, anxiety, depression, hopelessness, and quality of life. Outcomes are evaluated at multiple time points, including a three-month follow-up. The study monitors participant progress and collects data on their use of supportive care resources. The total participation period extends from baseline through follow-up assessments, with careful monitoring to understand the interventions impact on emotional well-being.

The EASE Study: Randomized Trial of a Novel Approach to Addressing Fear of Progression in Advanced Cancer