Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
NCT07225881

Eatwell Clinical Trial (R01)

Led by Drexel University · Updated on 2026-03-16

472

Participants Needed

1

Research Sites

220 weeks

Total Duration

On this page

Sponsors

D

Drexel University

Lead Sponsor

N

National Institutes of Health (NIH)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Cancer is a leading cause of death and will affect many people in their lifetimes. Organizations such as the American Cancer Society and the World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) have noted that dietary quality is a key factor influencing cancer risk, but most Americans do not meet these dietary guidelines for cancer prevention. The proposed study will enroll adults from the community (n=236 index participants, 236 household members; N = 472) who have low adherence to WCRF/AICR's four dietary guidelines. Participants will be randomized to either nutrition education or the Eatwell intervention. The Eatwell intervention content is focused on helping participants make healthier grocery shopping decisions, eat at home more often to take advantage of the optimal defaults present there, and learn how to navigate temptation when eating away from home. The findings will be relevant not only to the field of cancer prevention, but to the prevention of other diseases for which dietary quality is important.

CONDITIONS

Official Title

Eatwell Clinical Trial (R01)

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 or older
  • Access to technology to receive emails and join videoconferencing meetings
  • Ability to read and speak English
  • Willingness to be randomized and attend intervention sessions
  • Willingness to receive monthly emails and serve in a support role if assigned to Eatwell
  • Ability to visit a commercial laboratory for blood draws at study visits
  • Low adherence to WCRF/AICR's four dietary guidelines (score of 2 or less)
  • Share a household with an adult who consents, meets eligibility, and plans to stay for 18 months
  • Agree not to join another intervention study from this team during the next 18 months
  • Completion of all enrollment and baseline data tasks by self and household member
  • Have an email account regularly checked and willingness to use it for study communication
  • Weight at baseline 396 lbs or less due to scale limitations
Not Eligible

You will not qualify if you...

  • Medical or psychiatric conditions, including history of anorexia nervosa or bulimia nervosa, limiting ability to follow dietary recommendations
  • Psychiatric conditions making it difficult for household member to provide support
  • Currently taking medication that significantly changes appetite or eating behavior, including GLP-1 medications
  • Planning to enroll in another lifestyle program in the next 18 months
  • History of bariatric surgery
  • Currently pregnant or planning pregnancy in the next 18 months
  • Diagnosis of Type 1 Diabetes

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Drexel University

Philadelphia, Pennsylvania, United States, 19104

Actively Recruiting

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Research Team

R

Research Coordinator, BA

CONTACT

M

Meghan L Butryn, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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