Actively Recruiting
EBUS-TTFB vs EBUS-TBNA for Diagnosing Inadequate Lymph Node Specimens Based on MOSE
Led by Shanghai Chest Hospital · Updated on 2025-04-18
162
Participants Needed
3
Research Sites
39 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The study aims to compare the efficacy and safety of endobronchial ultrasound-guided transtunnel forceps biopsy to transbronchial needle aspiration in diagnosing inadequate lymph node specimens based on macroscopic on-site evaluation.
CONDITIONS
Official Title
EBUS-TTFB vs EBUS-TBNA for Diagnosing Inadequate Lymph Node Specimens Based on MOSE
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Chest imaging shows mediastinal or hilar lymphadenopathy with short axis 10 mm or larger
- EBUS-TBNA can be performed on these lymph nodes and previous conventional EBUS-TBNA with three needle passes resulted in inadequate specimens (macroscopic visible core less than 30 mm)
- Willing to participate in this clinical study and sign the informed consent form
You will not qualify if you...
- Enlarged lymph nodes identified as cystic or abscess
- Severe coagulopathy, insufficient anticoagulant or antiplatelet withdrawal time, or bleeding diathesis (platelets less than 50 x 10^9/L, INR greater than 1.3) not meeting bronchoscopy requirements
- Other contraindications to bronchoscopy or transbronchial biopsy such as severe cardiopulmonary insufficiency, intolerance to anesthesia, or endoscopic procedures
- Participation in another clinical trial within the past three months
- Vulnerable groups such as pregnant women
- Any other condition that the investigator considers inappropriate for participation in this study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 3 locations
1
The Fourth Affiliated Hospital of China Medical University
Shenyang, Liaoning, China, 110032
Not Yet Recruiting
2
Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine
Shanghai, Shanghai Municipality, China
Actively Recruiting
3
Huzhou Central Hospital
Huizhou, Zhejiang, China, 313000
Not Yet Recruiting
Research Team
J
Jiayuan Sun, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
DIAGNOSTIC
Number of Arms
2
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