Actively Recruiting

Phase Not Applicable
Age: 25Years - 45Years
All Genders
NCT07365033

Eccentric Exercise With Blood Flow Restriction vs Resistance Training for Lateral Epicondylitis

Led by Nimra Rafiq · Updated on 2026-02-05

40

Participants Needed

1

Research Sites

8 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This randomized controlled trial aims to compare the effectiveness of eccentric training combined with blood flow restriction (ECC+BFR) versus heavy slow resistance (HSR) training in patients with chronic lateral epicondylitis. The study will recruit 40 participants (accounting for 10% attrition), aged 25-45 years, from Sakina Memorial Hospital Sheikhupura and University of Lahore Teaching Hospital using convenience sampling. Participants will be randomly allocated into two groups: an interventional group receiving ECC+BFR and a control group undergoing HSR training. Both interventions will be administered three times per week for 8 weeks under professional supervision. Outcome measures including pain intensity (NPRS), patient-specific functional performance (PSFS), muscle strength, and hypertrophy will be assessed at baseline, 4 weeks, and 8 weeks. Data will be analyzed using SPSS, with appropriate parametric or non-parametric tests applied after checking data normality. Ethical approval will be obtained, informed consent will be secured, and participant confidentiality will be strictly maintained.

CONDITIONS

Official Title

Eccentric Exercise With Blood Flow Restriction vs Resistance Training for Lateral Epicondylitis

Who Can Participate

Age: 25Years - 45Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 25 and 45 years
  • Both male and female participants
  • Unilateral symptoms of lateral epicondylitis only
  • Clinical diagnosis confirmed by positive Cozen's and Mills' tests
  • Symptoms lasting more than 12 months indicating chronic lateral epicondylitis
Not Eligible

You will not qualify if you...

  • History of surgery or injection therapy for lateral epicondylitis within the past 6 months
  • Presence of other conditions like rheumatoid arthritis, cervical radiculopathy, or significant tendon tears
  • Contraindications to blood flow restriction therapy such as deep vein thrombosis, vascular disease, uncontrolled hypertension, or clotting disorders
  • Use of anticoagulants or long-term pain medications
  • Pregnancy
  • Psychological illness

AI-Screening

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Trial Site Locations

Total: 1 location

1

University of Lahore Teaching Hospital, Lahore

Lahore, Punjab Province, Pakistan, 54000

Actively Recruiting

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Research Team

N

Nimra Rafiq, MS MSK

CONTACT

M

Montiha Azeem, MSPTN

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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