Actively Recruiting
Echo-guided Transverse Abdominal Plane Block (TAP) in Anterior Lumbar Arthrodesis (ALIF): Randomized, Double-blind, Controlled Trial
Led by Clinique Saint Jean, France · Updated on 2026-01-06
80
Participants Needed
1
Research Sites
4 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating the effect of a transverse abdominal plane (TAP) block compared to a placebo in adults undergoing anterior lumbar spine surgery. The main goal is to determine whether the TAP block can reduce the need for pain medication after surgery. This randomized, double-blind, controlled trial is sponsored by Clinique Saint Jean, France, and focuses on patients having abdominal disc surgery at one or two levels. Participants will be randomly assigned to receive either an injection of levobupivacaine 2.5mg/ml as the TAP block or an injection of saline solution 2.5mg/ml as the placebo. Both injections are administered in the same way. The study will monitor pain medication use and pain levels for 72 hours after surgery. During the study, participants' consumption of pain medication will be closely recorded for three days after surgery. Pain will also be assessed using a visual analogue scale from 0 to 10 over the same period. Researchers will observe the effects of the TAP block on postoperative pain and analgesic use. The study will continue until October 2026, with safety and follow-up assessments included.
CONDITIONS
Brief Title
Echo-guided Transverse Abdominal Plane Block (TAP) in Anterior Lumbar Arthrodesis (ALIF)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient affiliated or entitled to a social security plan
- Patient who has been informed about the study and has co-signed a consent form
- Patients over 18 years of age scheduled for abdominal disc surgery on one or two levels
- Patient with ASA criteria 1, 2 and 3
You will not qualify if you...
- Patients with intolerance or contraindication to paracetamol, anti-inflammatory or morphine
- Patients allergic to local anesthetics
- Pregnant or breast-feeding patient
- Patient undergoing cancer or trauma surgery trauma
- Patient participating in another interventional study
- Patient with a history of lumbar arthrodesis
- Patient refusing to sign consent form
- Patient unable to give informed consent
- Patient under court protection, guardianship or trusteeship
- Patient not available for study follow-up
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Surgery day
Participants receive either an injection of levobupivacaine or a placebo tap block during their abdominal disc surgery.
1 visit (in-person)
Duration - 72 hours
Participants are monitored for pain and analgesic consumption for 72 hours after surgery.
Multiple assessments during 72 hours post-surgery
Trial Site Locations
Total: 1 location
1
Clinique St jean sud de france
Montpellier, France, 34430
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Similar Trials
Frequently Asked Questions
Have more questions? Get in touch with our team for quick support
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here