Study of Echocardiographic Tests to Detect Atrial Fibrillation in Adults With Stroke or TIA Using 7-Day ECG Monitoring

What this Trial Is About

Researchers are studying the accuracy of echocardiographic measurements to predict atrial fibrillation AF in patients who have experienced embolic stroke of undetermined source ESUS or transient ischemic attack TIA. The study focuses on testing the atrial electromechanical conduction time, measured as septal total atrial conduction time sPA-TDI, and the LaHAsPa-Score, which combines patient data and echocardiographic findings. The goal is to improve risk assessment and monitoring for AF in these patients. Participants undergo a 7-day ambulatory ECG monitoring after routine clinical diagnostics to detect AF. The study follows patients for up to two years to identify AF occurrences, including detection through implantable cardiac monitors or pacemakers if applicable. Other echocardiographic measures and diagnostic tests like 12-lead ECG and Holter monitoring are also compared to the main parameters. During the study, participants receive brain imaging to confirm stroke or TIA diagnosis and echocardiography to measure heart function. They are monitored using ECG devices over extended periods, with regular follow-up visits assessing stroke recurrence, anticoagulation therapy, and cardiovascular events. The primary outcome is detection of previously unrecognized AF during the initial 7-day ECG recording, with secondary outcomes monitored over two years.

Echocardiographic Predictors of Atrial Fibrillation