Actively Recruiting

All Genders
NCT07030062

Echocardiography Guided TAVR (Echo TAVR)

Led by Pan Xiangbin · Updated on 2025-06-19

20

Participants Needed

1

Research Sites

45 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Conventional transcatheter aortic valve replacement (TAVR) relies on fluoroscopic and contrast agents. However, in high-risk patients, exposure to ionizing radiation and contrast agents is contraindicated and undesirable. Echocardiography guidance TAVR can offer a feasible and safer strategy for TAVR.

CONDITIONS

Official Title

Echocardiography Guided TAVR (Echo TAVR)

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Symptomatic severe aortic stenosis confirmed by echocardiography and Doppler with mean gradient ≥40 mmHg, peak aortic velocity ≥4 m/s, and aortic valve area ≤1 cm2 (or indexed AVA ≤0.6 cm2/m2)
  • History of malignancy or high familial cancer risk, with refusal to undergo contrast- or radiation-guided procedures
  • Chronic kidney disease with refusal to receive contrast agents or radiation exposure
Not Eligible

You will not qualify if you...

  • Need for hybrid procedures or additional interventions on other cardiac malformations
  • Inoperable due to extremely high surgical risk or severe comorbid conditions
  • Untreated significant coronary vascular disease that can be treated with revascularization
  • Previous aortic valve replacement

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Fuwai Hospital

Beijing, China, 100037

Actively Recruiting

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Research Team

X

Xiangbin Pan, MD

CONTACT

F

Fengwen Zhang, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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