Actively Recruiting
ECoG BMI for Motor and Speech Control
Led by Karunesh Ganguly · Updated on 2026-05-05
3
Participants Needed
1
Research Sites
613 weeks
Total Duration
On this page
Sponsors
K
Karunesh Ganguly
Lead Sponsor
N
National Institute on Deafness and Other Communication Disorders (NIDCD)
Collaborating Sponsor
AI-Summary
What this Trial Is About
Test the feasibility of using electrocorticography (ECoG) signals to control complex devices for motor and speech control in adults severely affected by neurological disorders.
CONDITIONS
Official Title
ECoG BMI for Motor and Speech Control
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age greater than 21 years
- Limited upper limb use due to neurological disorders such as stroke, ALS, multiple sclerosis, cervical spinal cord injury, brainstem stroke, muscular dystrophy, myopathy, or severe neuropathy
- Severe disability causing loss of independence and inability to perform daily activities, defined by a score of 4 or higher on the Modified Rankin Scale
- At least 1 year since stroke or spinal cord injury symptom onset
- Living within a two-hour drive of UCSF
You will not qualify if you...
- Pregnant or breastfeeding
- Unable to understand or read English
- Unable to give consent
- Dementia based on history, exam, and Mini-Mental State Exam
- Active depression or other psychiatric illnesses such as general anxiety disorder, schizophrenia, bipolar disorder, OCD, or personality disorders
- History of suicide attempt or suicidal thoughts
- History of substance abuse
- Co-morbid conditions including ongoing anticoagulation, uncontrolled hypertension, cancer, or major organ failure
- Inability to comply with study follow-up visits
- Previous intracranial surgery
- History of seizures
- Immunocompromised state
- Active infection
- Presence of cerebrospinal fluid drainage system or active CSF leak
- Need for diathermy, electroconvulsive therapy, or transcranial magnetic stimulation to treat chronic condition
- Implanted electronic devices such as neurostimulators, pacemakers, defibrillators, medication pumps, or metallic foreign bodies in head or neck
- Allergies or known sensitivity to materials in the implant devices including silicone, titanium, platinum iridium, or nichrome
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of California San Francisco
San Francisco, California, United States, 94158
Actively Recruiting
Research Team
A
Adelyn Tu-Chan
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DEVICE_FEASIBILITY
Number of Arms
1
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