Actively Recruiting
Economic Incentives and vDOT for Latent Tuberculosis Infection
Led by Johns Hopkins University · Updated on 2026-05-04
399
Participants Needed
1
Research Sites
303 weeks
Total Duration
On this page
Sponsors
J
Johns Hopkins University
Lead Sponsor
N
National Institute of Allergy and Infectious Diseases (NIAID)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this study is to evaluate a novel and scalable intervention that combines Video Directly Observed Therapy (vDOT) and financial incentives to promote completion of treatment for latent tuberculosis. Adult participants who are initiating treatment for latent tuberculosis will be recruited from the Baltimore City Health Department. The primary hypothesis is that the incentive intervention will increase the percentage of participants that complete the treatment for latent tuberculosis above the completion rates of participants receiving usual care.
CONDITIONS
Official Title
Economic Incentives and vDOT for Latent Tuberculosis Infection
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 years old or older
- Diagnosed with latent tuberculosis and recommended for treatment by clinicians
- Reside in the Baltimore metropolitan area
- Speak English, Spanish, or a language with a short consent form approved by Johns Hopkins Medicine IRB
- Prescribed 3 months Isoniazid/Rifapentine, 3 months Isoniazid/Rifampin, or 4 months Rifampin for latent TB treatment
You will not qualify if you...
- Younger than 18 years old
- Diagnosed with active tuberculosis
- Prescribed an alternative treatment regimen for latent TB
- Pregnant women (as determined by clinical evaluation and urine pregnancy testing)
- Spoken language does not have a translated long or short consent form available
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Baltimore City Health Department, and Baltimore metropolitan area clinics and health departments
Baltimore, Maryland, United States, 21205
Actively Recruiting
Research Team
P
Principal Investigator
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
3
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