Actively Recruiting
Does Edema After Knee Arthroplasty Affect the Adjustment of TENS Amplitude
Led by Karamanoğlu Mehmetbey University · Updated on 2025-12-11
125
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
Sponsors
K
Karamanoğlu Mehmetbey University
Lead Sponsor
K
Karaman Training and Research Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
This research aims to compare the amplitude settings of three different frequency Transcutaneous Electrical Nerve Stimulation (TENS) modes—Conventional TENS, Low Frequency (LF) TENS, and High Frequency (HF) TENS—in patients undergoing total knee arthroplasty. The study investigates whether the electrical resistance of swollen (edematous) tissue affects the adjustment of TENS amplitude. Participants will be evaluated before surgery and compared with their contralateral (opposite) knee to understand these changes. Participants will receive TENS treatments using three different frequency modes. The researchers will record the amplitude levels at which participants feel tingling, clearly sense the current, experience maximum tolerance, or muscle contraction. These amplitude settings will be compared between the preoperative state and the postoperative state 2 to 3 days after surgery, as well as with the opposite knee. The study also considers the impact of the type of anesthesia and the amount of swelling on TENS amplitude settings. During the study, participants will be assessed before and after surgery through various measurements, including TENS amplitude at different sensation levels. The main outcomes measured are the differences in amplitude between pre- and post-surgery for each TENS mode within 2 to 3 days after surgery. Secondary assessments will examine how edema and anesthesia type affect these amplitudes. Safety and eligibility will be carefully monitored, and participants' pain and swelling levels will be observed throughout the study period.
CONDITIONS
Brief Title
Does Edema Affect the Adjustment of TENS Amplitude
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age �3E�3D 40 years
- Patients undergoing unilateral total knee arthroplasty
You will not qualify if you...
- Patients with scars in either knee area
- Patients who have previously had surgery on the opposite leg
- Patients undergoing surgery due to trauma or cancer
- Patients with sensory impairments
- Patients with excessive effusion and edema in the knee joints before surgery (e.g., inflammatory arthropathy, gonarthrosis exacerbation)
- Patients with mental impairment or poor general health interfering with TENS assessments
- Patients with any contraindication for TENS (allergy to electrodes, skin conditions or sensation impairments where electrodes are placed, pacemaker or implanted electrical device, epilepsy, pregnancy)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 1 day
Participants undergo preoperative measurements of TENS amplitude settings on the knee prior to surgery.
1 visit (in-person)
Duration - 2 to 3 days
Participants undergo unilateral total knee arthroplasty and receive standard postoperative care.
1 to 2 visits depending on postoperative status
Duration - 2 to 3 days
Participants are observed to assess the effects of edema and anesthesia type on TENS amplitude adjustments post-surgery.
1 to 2 visits for amplitude measurements
Trial Site Locations
Total: 1 location
1
Karaman Training and Research Hospital
Karaman, Turkey (Türkiye), 70200
Actively Recruiting
Research Team
A
Aynur Basaran, MD, Prof
Y
Yurdagul Bahran Mustu, MD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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