Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
ID04611022

Intervention to Educate and Improve Underserved Populations' Uptake and Completion of the HPV Vaccine Series

Led by University of Colorado, Denver · Updated on 2025-11-25

1000

Participants Needed

1

Research Sites

4 weeks

Total Duration

On this page

Sponsors

U

University of Colorado, Denver

Lead Sponsor

N

National Cancer Institute (NCI)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Researchers are evaluating an educational intervention designed to improve HPV vaccine uptake and completion among underserved populations, including adolescents and young adults. The study focuses on patients associated with Denver Health clinics and aims to increase knowledge and intentions regarding the HPV vaccine. The study uses a one-group post-test design to assess the intervention's effects on vaccine-related knowledge, intentions, and vaccine dose uptake, as well as clinic-level vaccine rates. The educational intervention includes toolkit materials developed by the National Cancer Institute, such as PowerPoint presentations, flyers, and posters, along with small media like an 8-minute video created using an entertainment-education approach. These materials convey information about HPV, HPV-related cancers, and the importance of completing the HPV vaccine series. The intervention is delivered by trained Community Health Educators to eligible participants, with tracking of vaccine doses received and referrals to vaccine programs or related services. Participants will complete a post-education survey at baseline to measure changes in knowledge and intentions. Researchers will monitor vaccine dose uptake at 3 and 6 months after the intervention and gather sociodemographic data related to vaccine uptake. Clinic-level HPV vaccine rates for adolescents and young adults will also be compared before and after the intervention, with quarterly assessments. The total study duration and participant involvement depend on vaccine dose tracking and referrals, with ongoing monitoring of vaccine completion.

CONDITIONS

Brief Title

Educate and Improve Underserved Populations' Uptake and Completion of the HPV Vaccine

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Be a Denver Health patient aged 18 to 26 years who has not started or completed the HPV vaccine series (3 doses)
  • Be a parent of a Denver Health adolescent patient aged 9 to 17 years who has not started or completed the HPV vaccine series (2 doses for ages 9-14, 3 doses for ages 14-17)
  • Speak English and/or Spanish
  • Willingness to comply with all study procedures and be available for the study duration
Not Eligible

You will not qualify if you...

  • Not meeting eligibility criteria, including inability to speak English or Spanish
  • Decisionally-challenged adults with cognitive or personality impairments or intoxication affecting consent or participation
  • Individuals from vulnerable populations such as inmates, homeless, pregnant women, or those with auditory impairment
  • Individuals under 18 years of age

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Outpatient Treatment

Duration - 1 day

Participants receive an educational intervention delivered by a trained community health educator to improve knowledge and intentions regarding the HPV vaccine.

1 baseline visit (in-person)

Follow-up

Duration - 6 months

Participants are followed to track uptake of one, two, or three HPV vaccine doses and referrals to care services to facilitate vaccine completion.

Visits at 3 and 6 months post intervention

Trial Site Locations

Total: 1 location

1

University of Colorado Hospital

Denver, Colorado, United States, 80237

Actively Recruiting

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Research Team

S

Sindy Gonzalez

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

PREVENTION

Number of Arms

1

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