Actively Recruiting

Phase Not Applicable
Age: 18Years - 39Years
All Genders
ID07174661

Educational Tools to Improve Early Advance Care Planning in Adolescents and Young Adults With Advanced Solid Tumors and High-Grade Brain Tumors

Led by Mayo Clinic · Updated on 2025-12-18

50

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating educational tools to improve early advance care planning (ACP) in adolescents and young adults (AYAs) aged 18 to 39 with advanced solid tumors or high-grade brain tumors. These cancers may have spread locally or to distant parts of the body and represent a significant cause of disease-related death among AYAs. The study aims to introduce key ACP concepts early in treatment to help patients clarify care goals, discuss end-of-life preferences, and complete advance directives. Participants will watch a brief, on-demand educational video about ACP at the start of the study and then, one month later, attend a tailored ACP appointment lasting about one hour. This appointment is conducted by either an AYA social worker or a palliative medicine physician assistant and focuses on reviewing an ACP guide designed specifically for AYAs and answering related questions. Additional activities include electronic health record reviews and survey completion. During the study, participants will be assessed for the feasibility of implementing early ACP and their satisfaction with the educational tools over up to one year. Researchers will also monitor advance directive completion rates and changes in ACP readiness and anxiety at baseline, four months, and seven months. The total study period allows for close monitoring and follow-up to better understand how these tools impact early ACP in this patient group.

CONDITIONS

Brief Title

Educational Tools for the Improvement of Early Advance Care Planning in Adolescents and Young Adults With Advanced Solid Tumors and High-Grade Brain Tumors

Who Can Participate

Age: 18Years - 39Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18-39 at initial cancer diagnosis
  • Diagnosed within 12 months with stage III/IV solid malignancy or high-grade brain tumor, including stage III/IV recurrence
  • Actively receiving primary oncologic care at Mayo Clinic Arizona
  • Able to read, understand, and speak English
  • Prior completion of advance directive does not exclude participation
Not Eligible

You will not qualify if you...

  • Age under 18 or over 39 at initial cancer diagnosis
  • Diagnosed with stage I/II solid malignancy, low-grade brain tumor, or hematologic malignancy
  • Not receiving primary oncologic care at Mayo Clinic Arizona
  • Unable to read, understand, and speak English
  • More than 12 months from initial diagnosis or advanced relapse, in survivorship, or on hospice
  • No access to internet or computer/smartphone

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 screening and enrollment visit

Outpatient Treatment

Duration - 1 month

Participants watch a brief, on-demand early advance care planning (ACP) educational video at baseline and then attend a 1-hour ACP appointment with a social worker or palliative medicine physician assistant one month later.

2 visits (1 baseline video viewing and 1 ACP appointment)

Long-term Monitoring

Duration - Up to 1 year

Participants complete surveys and their readiness and anxiety related to advance care planning are assessed at baseline, 4 months, and 7 months, with feasibility and satisfaction monitored for up to 1 year.

3 survey visits (at baseline, 4 months, and 7 months)

Trial Site Locations

Total: 1 location

1

Mayo Clinic in Arizona

Scottsdale, Arizona, United States, 85259

Actively Recruiting

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Research Team

S

Sey Oloyede

C

Clinical Trials Referral Office

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

1

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