Actively Recruiting
Effect of Acupuncture on Mild to Moderate Active Crohn's Disease
Led by Shanghai Institute of Acupuncture, Moxibustion and Meridian · Updated on 2025-05-14
60
Participants Needed
2
Research Sites
395 weeks
Total Duration
On this page
Sponsors
S
Shanghai Institute of Acupuncture, Moxibustion and Meridian
Lead Sponsor
F
Fudan University
Collaborating Sponsor
AI-Summary
What this Trial Is About
To observe the clinical effect of acupuncture on Crohn's disease (CD) and its influence on brain function activity and the TRY-KYN metabolism level, and to screen the brain image markers of acupuncture on CD
CONDITIONS
Official Title
Effect of Acupuncture on Mild to Moderate Active Crohn's Disease
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 16-70 years
- Mild or moderate active Crohn's disease (CDAI between 150 and 450)
- Not responsive, intolerant, dependent on, or refused treatment with mesalazine, glucocorticoid, immunomodulators, or anti-TNF alpha drugs
- Not taking medication or only taking prednisone (\u226415 mg/day for at least 1 month), azathioprine (\u22641 mg/kg/day for at least 3 months), methotrexate (\u226415 mg/week for at least 3 months), or mesalazine (\u22644 g/day for at least 3 months)
- No use of anti-TNF alpha or other agents within 3 months before the study
- Never had acupuncture before
- Signed informed consent
You will not qualify if you...
- Currently pregnant, recently pregnant, or breastfeeding
- Serious organic diseases
- Diagnosed with psychosis
- Taking antibiotics, probiotics, traditional Chinese medicine, or other drugs that may affect study results
- Severe skin diseases (e.g., erythema nodosum, pyoderma gangrenosum), eye diseases (e.g., iritis, uveitis), thromboembolic diseases, or serious extraintestinal manifestations
- Serious intestinal complications such as fistula, abscess, stenosis, obstruction, perianal abscess, gastrointestinal hemorrhage, or perforation
- Short bowel syndrome or abdominal/gastrointestinal surgery within past 6 months
- Skin diseases or defects in acupuncture/moxibustion areas preventing treatment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Shanghai Research Institute of Acupuncture and Meridian
Shanghai, Shanghai Municipality, China, 200030
Actively Recruiting
2
Guona Li
Shanghai, China, 2000
Actively Recruiting
Research Team
C
Chunhui Bao, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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