Actively Recruiting

Phase Not Applicable
Age: 18Years - 60Years
All Genders
NCT06487234

Effect of Acute ObeEnd Exposure on Factors Regulating Appetite

Led by Concordia University, Montreal · Updated on 2024-07-05

30

Participants Needed

1

Research Sites

38 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

n Canada, over 60% of adults are classified as overweight and obese resulting in a public health crisis including increasing health care costs and negatively impacting the well-being of many Canadians. To overcome these barriers, the ObeEnd device, manufactured by WAT Medical Enterprise, is a new and innovative wellness technology that uses electrical pulses to stimulate acupressure point PC6 to help control appetite. PC6 stimulation could potentially modulate appetite and restore gastric dysfunction, which are important factors that contribute to obesity. If PC6 electrostimulation facilitates the normalization of appetite and restoration of gastric dysfunction in those with obesity, then the device could be a potentially helpful aid to weight loss. To measure the change of appetite hormones and enzymes related to appetite regulation after using the ObeEnd device. The investigators hypothesize that, compared to placebo, acute electrostimulation of PC6 an acupuncture spot on the wrist for a 1 hour period will result in changes in enterogastric hormones in a direction that decreases appetite. This study will provide the first evidence of the acute effects of electrostimulation at PC6 on factors affecting body weight regulation providing insight into the utility of the ObeEnd device for weight control.

CONDITIONS

Official Title

Effect of Acute ObeEnd Exposure on Factors Regulating Appetite

Who Can Participate

Age: 18Years - 60Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • People with obesity (BMI>30kg/m2)
  • Generally healthy
  • Premenopausal females
Not Eligible

You will not qualify if you...

  • Past (<1 year) or present use of nicotine products
  • History of chronic disease or metabolic conditions
  • Females who are pregnant, less than 6 months postpartum, or breastfeeding
  • Diagnosed hepatic disease, renal impairment, uncontrolled hypothyroidism
  • Use of any medications that may affect study outcomes (e.g. hormone replacement therapy)

AI-Screening

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Trial Site Locations

Total: 1 location

1

Concordia University

Montreal, Quebec, Canada, H4B1R6

Actively Recruiting

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Research Team

S

Sylvia Santosa, PhD

CONTACT

A

Anjalee I Wanasinghee

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

DOUBLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

TREATMENT

Number of Arms

2

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