Actively Recruiting
Analgesic Efficacy of Adding Ultrasound Guided IPACK Block to Adductor Canal Block for Postoperative Pain Management After Excision of Tumors Around Knee: a Randomized Controlled Trial
Led by National Cancer Institute, Egypt · Updated on 2026-02-02
70
Participants Needed
1
Research Sites
4 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are evaluating the pain relief effects of combining an iPACK block with an Adductor Canal Block (ACB) after surgery to remove tumors around the knee. The study focuses on measuring the time until the first need for additional pain medication, the amount of morphine used after surgery, and pain levels using the visual analogue scale (VAS). This trial includes adult patients aged 18 to 65 years with specific physical health status undergoing knee tumor excision under spinal anesthesia. Participants are randomly assigned to one of two groups. One group receives both the ACB and the iPACK block, where local anesthetic is injected near nerves around the knee using ultrasound guidance. The control group has the ACB area identified by ultrasound but does not receive the nerve block; instead, they receive morphine and other pain medications as needed after surgery. Both groups are monitored for pain and medication use following the procedure. During the study, patients will be assessed for pain intensity at multiple time points within 24 hours after surgery and monitored for the time until they request additional pain relief. Morphine consumption and pain scores are recorded to compare the effectiveness of the treatments. Safety and overall recovery progress are observed, and the study is conducted with double-blind methods to reduce bias. Participation lasts through the immediate postoperative period to evaluate early pain management outcomes.
CONDITIONS
Brief Title
Effect of Adding Ultrasound Guided IPACK Block to Adductor Canal Block for Postoperative Pain in Knee Tumor Excision
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Willingness to comply with all study procedures and availability for the study duration
- American Society of Anesthesiologists (ASA) physical status II to IV
- Patients undergoing excision of tumors around the knee under spinal anesthesia
- Age between 18 and 65 years
You will not qualify if you...
- Patient refusal to participate
- Presence of neuromuscular disorders
- Allergy to local anesthetics
- Previous history of knee surgery
- History of prior knee infection
- Contraindications to spinal anesthesia such as coagulopathies or severe aortic stenosis
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - 24 hours postoperative
Participants receive either an adductor canal block with an additional ultrasound guided IPACK block or are observed without block as part of pain management after knee tumor excision surgery under spinal anesthesia.
1 baseline visit and multiple assessments within 24 hours after surgery
Trial Site Locations
Total: 1 location
1
National cancer institute
Cairo, Egypt, 11769
Actively Recruiting
Research Team
N
Norma Osama Abdallah Zayed, MD
F
Fady Attef, MSc
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
PREVENTION
Number of Arms
2
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