Study of Adenotonsillectomy Surgery on Spinal Curve Changes in Children Aged 6 to 15 With Mild Sleep-Disordered Breathing and Scoliosis

What this Trial Is About

Researchers are studying the effect of adenotonsillectomy AT surgery on spinal curvature in children aged 6 to 15 years who have mild sleep-disordered breathing SDB and scoliosis. The study also looks at whether AT can prevent new scoliosis in children with SDB. This is a randomized controlled trial aiming to understand if treating SDB with AT influences the progression or onset of scoliosis, conditions that often occur together and may impact child development and spinal alignment. Participants are randomly assigned to one of two groups. One group will undergo adenotonsillectomy surgery within four weeks of enrollment, which involves removing the tonsils and adenoids to treat SDB. The other group will receive watchful waiting with supportive care, including healthy sleep information and clinical referrals, with surgical re-evaluation after 12 months. Follow-up visits occur every six months for at least two years to monitor changes in spinal curvature and related health measures. During the study, children will have scoliosis screening, sleep assessments, and biomarker tests at baseline and regular intervals. Researchers will measure scoliosis curve angle, angle of trunk rotation, sleep quality, circadian rhythms, body mass index, and changes in serum biomarkers and gene expression. This monitoring will help determine how AT impacts scoliosis progression and overall health in children with mild SDB.

Effect of Adenotonsillectomy on Spinal Curve Magnitude in Children With Sleep-Disordered Breathing