Actively Recruiting
Effect of Adenotonsillectomy on Spinal Curve Magnitude in Children With Sleep-Disordered Breathing
Led by Second Affiliated Hospital of Wenzhou Medical University · Updated on 2026-01-12
160
Participants Needed
1
Research Sites
159 weeks
Total Duration
On this page
Sponsors
S
Second Affiliated Hospital of Wenzhou Medical University
Lead Sponsor
T
The Children's Hospital of Zhejiang University School of Medicine
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study aims to determine the effect of adenotonsillectomy (AT) surgery on the progression of spinal curvature in children with mild sleep-disordered breathing (SDB) and concurrent scoliosis, as well as its potential role in preventing the de novo development of scoliosis in children with SDB.
CONDITIONS
Official Title
Effect of Adenotonsillectomy on Spinal Curve Magnitude in Children With Sleep-Disordered Breathing
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 6 and 15 years
- Diagnosed with mild sleep-disordered breathing (OAHI ≤5 events/hour) confirmed by polysomnography within 6 months
- Habitual obstructive breathing symptoms (e.g., snoring, mouth-breathing, witnessed apneas) occurring more than 3 nights per week
- Tonsillar hypertrophy graded 2 or higher and suitable for adenotonsillectomy after ENT evaluation
- Radiographic screening for idiopathic scoliosis completed at first clinic visit
- Skeletally immature with spinal Cobb angle less than 40 degrees
- Informed consent and assent provided by participant and guardian
You will not qualify if you...
- Unwillingness or inability to follow study procedures
- Planning to move outside the study area within 24 months
- Previous tonsillectomy or adenoidectomy
- Recurrent tonsillitis requiring immediate adenotonsillectomy
- Severe obstructive sleep apnea (OAHI >10) or significant low oxygen needing immediate CPAP
- Severe chronic conditions affecting outcomes, including syndromic, neuromuscular, or congenital causes of scoliosis
- History of spine surgery or major spinal injury
- Presence of spinal tumor
- Leg length difference greater than 20 mm
- Severe cardiopulmonary diseases like cystic fibrosis or congenital heart disease
- Significant heart rhythm problems found on sleep study
- Bleeding disorders or sickle cell disease
- Uncontrolled diabetes, narcolepsy, or asthma
- Genetic, craniofacial, neurological, or psychiatric conditions affecting airway or participation
- Severe obesity with BMI z-score 3 or higher
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
The Second Affiliated Hospital of Wenzhou Medical University,
Wenzhou, Zhejiang, China, 325000
Actively Recruiting
Research Team
X
Xiangyang Wang, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here