Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT06278285

Effect of Agonist GLP1 on Adipose Tissue in Patients Undergoing Bariatric Surgery

Led by Centre Hospitalier Universitaire de Nice · Updated on 2026-03-27

40

Participants Needed

1

Research Sites

156 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Normalizing weight gain and preventing the redistribution of body fat is a major health issue, and could help prevent the onset of various symptoms of metabolic syndrome. Above all, it is important to understand the mechanisms by which these different treatments affect adipose tissue. To this end, the investigators will first study the impact of GLP-1 analogues on adipose tissue. The main objective is to show that subjects treated with a GLP-1 agonist have a significant change in their oxytocin levels compared with subjects not treated with a GLP-1 agonist.

CONDITIONS

Official Title

Effect of Agonist GLP1 on Adipose Tissue in Patients Undergoing Bariatric Surgery

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient over 18 years of age
  • Patient able to read and understand the information/consent leaflet
  • Patient with BMI > 35 with at least one comorbidity, or BMI > 40
  • Indication for digestive surgery validated in a multidisciplinary consultation meeting and prior agreement accepted by the CPAM
  • Membership of a social security scheme
  • Patient's signed informed consent
  • For subjects in the GLP-1 analogue group: GLP-1 analogue taken for at least 3 months
  • For non-GLP-1 analogue group: never taken GLP-1 analogues
Not Eligible

You will not qualify if you...

  • Pregnant or breast-feeding women
  • Vulnerable patients (under guardianship)
  • Patients deprived of liberty

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

CHU de Nice - Hôpital de l'Archet

Nice, Alpes-maritimes, France, 06200

Actively Recruiting

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Research Team

R

ROUX Christian, PhD

CONTACT

I

Iannelli Antonio, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

DIAGNOSTIC

Number of Arms

2

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