Actively Recruiting
"Effect of Albumin Combined With Furosemide in Critically Ill Patients With Fluid Overload: Impact on Urine Output and Renal Function"
Led by Jose J Zaragoza, MD MSc · Updated on 2026-02-18
56
Participants Needed
1
Research Sites
73 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study aims to compare the effectiveness of furosemide alone versus the combination of furosemide plus albumin in critically ill adult patients with fluid overload. The trial evaluates whether co-administration of albumin enhances diuretic response compared with standard furosemide therapy. The primary outcomes include urine output at 2 hours, changes in renal perfusion markers, and biochemical parameters. Secondary outcomes include changes in mean arterial pressure, electrolyte balance, and renal resistance index. The study seeks to determine whether adding albumin provides a clinically meaningful improvement in diuresis and renal function compared with furosemide monotherapy.
CONDITIONS
Official Title
"Effect of Albumin Combined With Furosemide in Critically Ill Patients With Fluid Overload: Impact on Urine Output and Renal Function"
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults 218 years or older admitted to the ICU without mechanical ventilation
- Starting diuretic therapy for the first time during the ICU stay due to fluid overload as determined by the treating physician
You will not qualify if you...
- Patients or family members who refuse participation
- Patients receiving palliative care
- Patients with kidney failure requiring renal replacement therapy
- Patients currently in another clinical research study
- Patients with signs of low blood volume or dehydration
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
76000
Querétaro City, Querétaro, Mexico, 26089
Actively Recruiting
Research Team
A
Alina Elizabeth Arechiga Casas, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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