Actively Recruiting
Effect of Albumin Replacement on Oxygen Delivery in Sepsis Patients
Led by Samsun University · Updated on 2025-07-03
45
Participants Needed
1
Research Sites
47 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Fluid resuscitation is a critical component of sepsis treatment. Research has shown that intravenous (IV) fluid therapy in sepsis positively impacts cardiac output and thereby oxygen (O2) delivery through a complex interaction of central venous pressure, right atrial pressure, venous resistance, ventricular compliance, cardiac contractility, and systemic vascular resistance. The 2021 sepsis prevention guidelines recommend balanced crystalloids as first-line therapy. However, no studies in the literature have evaluated the effect of albumin on O2 delivery. In our study, the investigators aim to assess the impact of albumin replacement on O2 delivery in sepsis patients in the intensive care unit.
CONDITIONS
Official Title
Effect of Albumin Replacement on Oxygen Delivery in Sepsis Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Followed up with a diagnosis of sepsis
- 18 years of age or older
- Diagnosed with hypo-albuminemia after receiving more than 4 liters of fluid resuscitation per day
- Underwent albumin replacement
You will not qualify if you...
- Consent not given by the patient or guardian
- Initial cause of shock is hypovolemic, cardiogenic, or obstructive shock
- Pregnancy or suspected pregnancy
- Peripheral limb or severe organ ischemia with peripheral artery disease
- Cardiac functions cannot be evaluated well by transthoracic echocardiography
- Patients who died within 24 hours after intensive care admission
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Samsun University
Samsun, Ilkadım, Turkey (Türkiye), 55100
Actively Recruiting
Research Team
G
gamze MD ertaş, specialist
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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