Actively Recruiting

Phase Not Applicable
Age: 18Years - 75Years
All Genders
NCT06403280

The Effect of Alcohol on Common Tremor Syndromes

Led by Medical University of Graz · Updated on 2025-09-29

45

Participants Needed

1

Research Sites

95 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The aim of this interventional study is to compare the response to alcohol in patients with essential tremor (ET), essential tremor plus (ETplus), dystonic tremor (DT), tremor associated with dystonia (TaD) and tremor in Parkinson´s disease (PD). The main question to be answered is: • Is there a difference in the objective alcohol responsiveness of patients with ET, DT, TaD and PD? Participants will receive either vodka with rum-flavoured orange juice with a target blood alcohol of 0.4 ‰ or a non-alcoholic rum-flavoured orange juice (vice versa on the second study day). Before and 30, 60 an 120 minutes after the study drink the participants will undergo a clinical examination of the tremor and accelerometry will be performed. Researchers will compare alcohol and placebo in a randomized cross over way to see if the effect of alcohol on tremor exceeds the placebo effect.

CONDITIONS

Official Title

The Effect of Alcohol on Common Tremor Syndromes

Who Can Participate

Age: 18Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of Parkinson's disease, dystonic tremor, tremor associated with dystonia, essential tremor, or essential tremor plus based on clinical criteria
  • Presence of tremor in the upper extremities
  • Ability to bring an accompanying person to both study visits
Not Eligible

You will not qualify if you...

  • Unwillingness to abstain from driving on both study days
  • Diseases that prohibit alcohol ingestion
  • History of alcohol abuse
  • Pregnancy

AI-Screening

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Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Medical University of Graz

Graz, Styria, Austria, 8010

Actively Recruiting

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Research Team

P

Petra Schwingenschuh, MD

CONTACT

D

Daniela Kern, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

TRIPLE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

DIAGNOSTIC

Number of Arms

2

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