Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
NCT06676813

Effect of Alternate Day Fasting Over Standard Medical Management Alone to Reverse Non-alcoholic Steatohepatitis.

Led by Institute of Liver and Biliary Sciences, India · Updated on 2024-11-07

72

Participants Needed

1

Research Sites

52 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The aims of this study are as follows: To compare the role of alternate-day fasting over standard medical management alone to reverse NASH.

CONDITIONS

Official Title

Effect of Alternate Day Fasting Over Standard Medical Management Alone to Reverse Non-alcoholic Steatohepatitis.

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18-65 years with BMI 25-40 kg/m3 and controlled liver fat (CAP more than 290)
  • Stable weight in the last 3 months with less than 5 kg variation
  • Imaging shows steatotic liver disease with liver stiffness less than 14 kPa
  • Histologically confirmed NASH or MASH with fibrosis stage up to F3
  • Willingness to participate in the study and provide consent
Not Eligible

You will not qualify if you...

  • Liver stiffness greater than 14 kPa or fibrosis stage above F3
  • Diabetes with HbA1c above 8.5%
  • Presence of other active liver diseases like hepatitis B or C, or alcoholic liver disease
  • Diagnosis of cirrhosis, liver cancer, or any other malignancy
  • Chronic kidney disease, cardiovascular disorders, or uncontrolled hypertension
  • Chronic infections or inflammatory diseases
  • Use of weight loss medications such as semaglutide
  • Pregnant or breastfeeding women or those planning pregnancy
  • Unwillingness to participate or inability to provide consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Institute of Liver and Biliary Sciences

Delhi, India, 110070

Actively Recruiting

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Research Team

B

Babu Lal Meena, DM Hepatology

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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