Actively Recruiting
Effect of Anticoagulant Therapy on Endometrial Receptivity and Pregnancy Outcomes in Infertility
Led by Tang-Du Hospital · Updated on 2026-03-27
300
Participants Needed
1
Research Sites
121 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this prospective observational cohort study is to evaluate the effect of routine clinical anticoagulant therapy on endometrial receptivity and subsequent pregnancy outcomes in women with infertility. Researchers will utilize an ultrasound multimodal system to systematically assess endometrial parameters, including thickness, morphology, peristalsis, and blood flow indices. The study aims to enroll approximately 300 infertile women aged 20 to 45 years. Participants will be observed and grouped based on whether they receive anticoagulant medications, such as aspirin or heparin sodium, as part of their standard clinical care. The study will track ultrasound-based receptivity indicators and follow up on pregnancy status and outcomes at 45 and 90 days of gestation. This study is purely observational, and all clinical treatment decisions are made independently of the study protocol.
CONDITIONS
Official Title
Effect of Anticoagulant Therapy on Endometrial Receptivity and Pregnancy Outcomes in Infertility
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Female patients aged 20 to 45 years
- Diagnosed with infertility and planning embryo transfer or monitored conception cycles
- Have complete baseline clinical data and agree to multimodal ultrasound evaluation during implantation window
- Voluntarily agree to participate and signed informed consent for data collection
You will not qualify if you...
- Congenital uterine malformations that significantly alter the endometrial cavity
- Untreated severe intrauterine lesions such as submucosal fibroids, severe adhesions, or endometrial polyps
- Severe systemic diseases including serious liver or kidney dysfunction or malignant tumors
- Known severe bleeding disorders or contraindications to anticoagulant medications
- Unable to cooperate with transvaginal ultrasound or complete pregnancy follow-up
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Tangdu Hospital, Air Force Medical University
Xi'an, Shaanxi, China, 710038
Actively Recruiting
Research Team
L
Li Zhang, MD
CONTACT
Z
Zhengjun Ma, MM
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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