Comparing Antiseptic Irrigation With Irrisept Versus Normal Saline During Fasciocutaneous Flap Surgery for Pilonidal Disease Using Myriad Extracellular Matrix Implantation

What this Trial Is About

Pilonidal disease is a long-lasting condition causing painful inflammation and infection near the top of the buttocks, often requiring surgery. This research compares two different wound rinses used before closing the surgical flap in patients with pilonidal disease to see if one can reduce post-surgery infections and wound problems. The study focuses on patients undergoing flap closure along with implantation of an extracellular matrix to support healing. Participants will receive either an antiseptic rinse called Irrisept, containing 0.05% chlorhexidine gluconate, or the standard rinse using sterile normal saline during their flap-based closure surgery. Both treatments are applied during surgery right before the wound is closed, and all other surgical care follows usual practices. The study groups are randomly assigned to compare the effects of these two rinses on surgical outcomes. During the study, participants will be monitored for up to 3 months after surgery to assess wound healing progress and any complications such as infection, fluid buildup, or wound separation. Researchers will track treatment-emergent adverse events and measure time to complete wound healing. This follow-up helps evaluate the safety and effectiveness of the rinse solutions used during surgery.

Effect of Antiseptic Irrigations With 0.05% Chlorhexidine Gluconate (Irrisept) Versus Normal Saline on Fasciocutaneous Flap-Based Closure of Pilonidal Disease