Study of Low-Dose Aspirin to Prevent Recurrences of Recurrent Acute Pancreatitis in Patients Aged 14 to 80

What this Trial Is About

This research aims to explore the effects of taking 100mg aspirin daily on reducing the recurrence of acute pancreatitis, a condition where patients have two or more episodes of inflammation in the pancreas. Recurrent acute pancreatitis is linked to higher risks of complications, lower quality of life, and increased healthcare costs. Current effective prevention methods exist mainly for biliary and alcoholic causes, but not for other causes such as idiopathic pancreatitis. Participants in the study will receive one 100mg aspirin tablet daily by mouth for two years to assess whether aspirin can reduce the frequency of recurrent acute pancreatitis episodes. This is a prospective cohort study sponsored by the Air Force Military Medical University in China. Aspirin is being studied for its possible role in inhibiting the inflammatory process involved in pancreatitis. During the two-year follow-up, researchers will monitor the time between pancreatitis episodes, the number of episodes, their severity, hospital stay lengths, and rates of chronic pancreatitis and new diabetes onset. They will also track aspirin usage, mortality rates, and any adverse events related to aspirin. Participants will be regularly evaluated to assess these outcomes and ensure safety throughout the study period.

The Effect of Aspirin on Recurrent Acute Pancreatitis