Actively Recruiting

Phase 2
Age: 4Years - 16Years
All Genders
NCT07456488

The Effect of 0.01% Atropine Eye Drops on Axial Length and Refraction in Myopic Children Compared to a Control Group

Led by Liaquat National Hospital & Medical College · Updated on 2026-03-06

60

Participants Needed

1

Research Sites

41 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

In this study, atropine 0.01% eye drops will be given to myopic children once at night daily for 6 months as compared to a control group to see the effect on axial length and refraction

CONDITIONS

Official Title

The Effect of 0.01% Atropine Eye Drops on Axial Length and Refraction in Myopic Children Compared to a Control Group

Who Can Participate

Age: 4Years - 16Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Children aged 4-16 years
  • Both genders
  • Myopia with baseline spherical equivalent refraction of -1.00 diopters or more
  • Astigmatism less than or equal to -2.50 diopters
  • No medical history predisposing to severe myopia such as Marfan syndrome, Stickler syndrome, or retinopathy of prematurity
  • No abnormal ocular refractive anatomy like keratoconus, lenticonus, or spherophakia
  • No history of vision-threatening ocular diseases or previous intraocular surgery
  • No current or previous use of atropine, pirenzipine, contact lenses, or other treatments affecting myopia progression
Not Eligible

You will not qualify if you...

  • Astigmatism greater than or equal to 2.5 diopters
  • Anisometropia greater than 1 diopter
  • Best corrected visual acuity less than 0.5 (6/12)
  • Prior intraocular surgery
  • Allergy to atropine eye drops
  • Systemic diseases associated with myopia such as Marfan syndrome or Stickler syndrome
  • History of cardiac or significant respiratory diseases
  • Lack of consent for participating in the study

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

LiaquatNHMC

Karachi, Sindh, Pakistan

Actively Recruiting

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Research Team

H

Hina Nadeem, MBBS

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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