Actively Recruiting
The Effect of Bariatric Surgery on Insulin Sensitivity and Energy Metabolism
Led by German Diabetes Center · Updated on 2025-01-10
450
Participants Needed
1
Research Sites
847 weeks
Total Duration
On this page
Sponsors
G
German Diabetes Center
Lead Sponsor
D
Dep.of General-, Visceral- and Pediatric Surgery, HHU, Duesseldorf, Germany
Collaborating Sponsor
AI-Summary
What this Trial Is About
The purpose of this study is: 1. To explore to what extent insulin sensitivity, energy metabolism and ectopic lipid storage can be improved by bariatric surgery 2. To explore to what extent hepatic and muscular disorders of energy metabolism occur in patients with obesity (degree 2-3) 3. To explore whether the steato liver occurring in patients with obesity (degree 2-3) is associated with the degree of liver inflammation
CONDITIONS
Official Title
The Effect of Bariatric Surgery on Insulin Sensitivity and Energy Metabolism
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Aged 20 years to 70 years
- BMI 20-25 kg/m2 for normal-weight group
- BMI 35-39.9 kg/m2 for obesity grade 2
- BMI greater than 40 kg/m2 for obesity grade 3
You will not qualify if you...
- Acute illness within 2 weeks before examination
- Autoimmune or immune disorders with leukocytes less than 5000/µl
- Kidney problems with creatinine over 1.5 mg/dl
- Heart disease or history of heart attack
- Anemia with hemoglobin less than 12 g/l or recent blood donation within 4 weeks
- Participation in another clinical trial within last 2 weeks
- Use of pharmacological immunotherapy (Cortisol, Antihistamines, ASS)
- Thyroid disorders
- Glitazone therapy
- Pregnancy, lactation, or menstruation
- Smoking, alcohol, or drug abuse
- Psychiatric disorders
- Risk for or diagnosed HIV/AIDS or Hepatitis B/C
- Liver diseases not caused by non-alcoholic steatohepatitis
- Night shift work or irregular sleep patterns
- Poor wound healing or clotting problems
- Allergy to local anesthetics
- Malignant cancer
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
German Diabetes Center
Düsseldorf, North Rhine-Westphalia, Germany, 40225
Actively Recruiting
Research Team
S
Sabine Kahl, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here