Actively Recruiting
Effect of Benzalkonium Chloride Preserved and Preservative-free Latanoprost Eye Drops on Conjunctival Goblet Cells
Led by Rigshospitalet, Denmark · Updated on 2023-11-18
28
Participants Needed
2
Research Sites
278 weeks
Total Duration
On this page
Sponsors
R
Rigshospitalet, Denmark
Lead Sponsor
L
Laboratoires Thea
Collaborating Sponsor
AI-Summary
What this Trial Is About
a randomized, investigator-blind, interventinal study will compare the effect of benzalkonium-chloride (BAK) preserved and preservative-free (PF) eye drops on conjunctival goblet cells.
CONDITIONS
Official Title
Effect of Benzalkonium Chloride Preserved and Preservative-free Latanoprost Eye Drops on Conjunctival Goblet Cells
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age over 18 years
- Danish speaking
- Diagnosed with open angle glaucoma or ocular hypertension
- Average intraocular pressure equal to or above 22 mmHg
You will not qualify if you...
- History of significant eye disease other than open angle glaucoma and ocular hypertension
- Treatment with steroids within the last 3 months before inclusion
- Significant untreated systemic diseases such as hypertension, heart failure, diabetes, stroke, lung disease, and autoimmune diseases unless well treated or not requiring treatment
- Pregnant or breastfeeding women
- Women using unsafe contraception
- Allergy to trial medications
- Inability to cooperate in eye examinations
- Presence of ocular surface defects
- Need for multiple glaucoma treatments (polytherapy)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 2 locations
1
Department of ophthalmology, rigshospitalet.glostrup
Glostrup Municipality, Danmark, Denmark, 2600
Not Yet Recruiting
2
Department of drug design and pharmacology, University of Copenhagen
Copenhagen, Denmark, 2100
Actively Recruiting
Research Team
A
Anne Nagstrup, MD
CONTACT
M
Miriam Kolko, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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