Actively Recruiting
The Effect of Beta-blocker on Chronotropic Response and Cardiorespiratory Fitness in Patients With Atrial Fibrillation
Led by National Taiwan University Hospital · Updated on 2025-03-24
40
Participants Needed
1
Research Sites
26 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This is a prospective study to evaluate changes in exercise capacity and chronotropic response to exercise before and after beta-blocker dosage reduction in patients with atrial fibrillation (AF).
CONDITIONS
Official Title
The Effect of Beta-blocker on Chronotropic Response and Cardiorespiratory Fitness in Patients With Atrial Fibrillation
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Over 20 years of age
- Clinically stable with persistent atrial fibrillation
- Using beta-blocker for rate control without dosage changes for at least 3 months
- Resting heart rate below 80 beats per minute
- Left ventricular ejection fraction greater than 50%
You will not qualify if you...
- Using beta-blockers for reasons other than rate control of atrial fibrillation
- Unable to perform cardiopulmonary exercise testing
- Contraindications for cardiopulmonary exercise testing based on American College of Sports Medicine guidelines
- Having an implantable cardioverter defibrillator or pacemaker
- Pregnant
- Unable to provide informed consent
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
National Taiwan University Hospital
Taipei, Taiwan, 100
Actively Recruiting
Research Team
H
Hung-Jui Chuang, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
2
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