Actively Recruiting
Effect of Bilateral Ultrasound-Guided TAP Block on Quality of Recovery in Cesarean Delivery Patients Receiving Intrathecal Morphine
Led by MEHMET GÖKHAN TAFLAN · Updated on 2026-04-02
150
Participants Needed
1
Research Sites
36 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This prospective, assessor-blinded observational cohort study will investigate the effect of adding bilateral ultrasound-guided transversus abdominis plane (TAP) block to standard intrathecal morphine (ITM) analgesia on the quality of recovery in women undergoing elective cesarean delivery under spinal anesthesia. All participants will receive ITM as part of routine spinal anesthesia. The TAP group will receive an additional bilateral ultrasound-guided TAP block at the end of surgery, while the control group will not receive any additional block. Both groups will receive standardized postoperative analgesia with intravenous patient-controlled analgesia (IV PCA). The primary outcome is the quality of recovery at 24 hours postoperatively, measured using the validated Obstetric Quality of Recovery-10 (ObsQoR-10) questionnaire. Secondary outcomes include Numerical Rating Scale (NRS) pain scores, time to first breastfeeding, time to mobilization, time to hospital discharge, and total opioid consumption in the first 24 hours after surgery. Outcome assessors will be blinded to group allocation. The study aims to determine whether TAP block enhances functional recovery, reduces pain, and decreases analgesic requirements when used alongside ITM in cesarean delivery patients.
CONDITIONS
Official Title
Effect of Bilateral Ultrasound-Guided TAP Block on Quality of Recovery in Cesarean Delivery Patients Receiving Intrathecal Morphine
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Female patients aged 18-45 years
- Singleton pregnancy
- ASA physical status II-III
- Scheduled elective lower segment cesarean delivery under spinal anesthesia with intrathecal morphine
- Able to understand study procedures and provide written informed consent
- Able to use intravenous patient-controlled analgesia (IV PCA)
- Able to complete Obstetric Quality of Recovery-10 assessments (with assistance if needed)
You will not qualify if you...
- Contraindication to spinal anesthesia or TAP block (e.g., injection site infection, coagulopathy, allergy to local anesthetics)
- Chronic opioid use or intolerance to opioid/alfa-2 agonists
- Severe preeclampsia, HELLP syndrome, or significant hepatic or renal impairment
- Urgent or emergency cesarean section (Category 1)
- Cognitive impairment or communication difficulties preventing assessment
- Prior major abdominal surgery except previous cesarean delivery
- Body mass index (BMI) greater than 40 kg/m²
- Major psychiatric illness affecting pain perception or recovery
AI-Screening
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Trial Site Locations
Total: 1 location
1
Samsun University Training and Research Hospital
Samsun, Samsun, Turkey (Türkiye), 55090
Actively Recruiting
Research Team
M
Mehmet Gökhan Taflan, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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