Actively Recruiting
Effect of Bone Augmentation Simultaneous to Implant Removal on the Prognosis of Reimplantation at the Same Site
Led by The Dental Hospital of Zhejiang University School of Medicine · Updated on 2025-07-22
40
Participants Needed
3
Research Sites
21 weeks
Total Duration
On this page
Sponsors
T
The Dental Hospital of Zhejiang University School of Medicine
Lead Sponsor
H
Hospital of Stomatology, Wuhan University
Collaborating Sponsor
AI-Summary
What this Trial Is About
This research aims to investigate how bone augmentation performed at the same time as implant removal affects the success of reimplantation at the same site. The study compares clinical and radiographic indicators between patients who receive bone substitutes during implant removal and those who experience natural healing without bone augmentation. It also reviews past cases of implant failure to identify factors influencing bone healing and reimplantation outcomes. Participants are randomly assigned to one of two groups: one group receives bone substitutes placed in the socket during implant removal, followed by reimplantation after six months of healing; the other group undergoes natural healing after implant removal without bone augmentation. This randomized, double-blind approach helps evaluate the impact of simultaneous bone augmentation on the prognosis of reimplantation. During the study, measurements such as ridge height, ridge width, bone plate thickness, and bone mineral density are recorded before and six months after implant removal. Implant insertion torque, survival rates, probing depth, bleeding on probing, and marginal bone loss are assessed at six and twelve months after restoration. Participants will be closely monitored through follow-up visits to track these outcomes and ensure comprehensive evaluation of bone healing and implant success over time.
CONDITIONS
Brief Title
Effect of Bone Augmentation Simultaneous to Implant Removal on the Prognosis of Reimplantation at the Same Site
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age greater than 18 years
- Implant failure requiring removal
- Plan to reimplant in the same site
- Periodontal health or stabilized periodontitis after treatment
You will not qualify if you...
- Uncontrolled metabolic diseases
- Taking medications that affect bone metabolism
- Implant detached at the time of consultation
- Do not consent to reimplant in the same site
- Unwillingness to participate in follow-up
- Other conditions unsuitable for implant therapy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 6 months
Participants undergo implant removal with or without bone augmentation. Those receiving bone augmentation have bone substitutes placed simultaneously, followed by a 6-month healing period before reimplantation.
1 procedure visit followed by observation during healing
Duration - 12 months
Participants receive reimplantation surgery and are monitored for implant survival and oral health indicators up to 12 months after restoration.
Visits at 6 months and 12 months after restoration
Trial Site Locations
Total: 3 locations
1
Hospital of Stomatology, Wuhan University
Wuhan, Hubei, China, 430079
Actively Recruiting
2
The Affiliated Stomatology Hospital of Zhejiang University School of Medicine
Hangzhou, Zhejiang, China, 310000
Actively Recruiting
3
Shanghai Stomatological Hospital
Shanghai, China, 200001
Actively Recruiting
Research Team
M
Misi Si
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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