Actively Recruiting
The Effect Of Botox In Patients With Gummy Smile With And Without Zinc And Phytase Supplementation.
Led by Cairo University · Updated on 2024-09-23
36
Participants Needed
1
Research Sites
52 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Participants with esthetic concern of excessive gingival display who meets the inclusion criteria, will be carried out including history taking, clinical examination and initial therapy. The initial therapy will consist of periodontal treatment (phase I therapy) including supragingival scaling, subgingival debridement if needed. The mechanical plaque control instructions for each patient include brushing and interdental cleaning techniques. Patients who have inadequate crown length and width ratio or short clinical crown will receive esthetic crown lengthening procedure to adjust gingival levels before being included in this study. Patients in the intervention group I will take zinc gluconate 50 mg 1 per day to increase zinc level with phytase supplement 176mg (800FTU) 2 tablets per day to give the maximum absorption of zinc, both supplements will be given for 4 days before botulinum toxin injections. Patients in the intervention group II will take zinc gluconate 50 mg 1 per day to increase zinc level, 4 days before botulinum toxin injections. Patients in the control group will receive the Botulinum toxin injections only Clinical photographs will be taken at baseline, 2 weeks, 1 month, 3 months postoperatively.
CONDITIONS
Official Title
The Effect Of Botox In Patients With Gummy Smile With And Without Zinc And Phytase Supplementation.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with excessive gingival display greater than 3 mm and normal clinical crown dimensions
- Adults aged 18 to 60 years
- Non-smokers
- Systemically healthy individuals
- Patients with hypermobile lip and mild vertical maxillary excess
You will not qualify if you...
- Severe vertical maxillary excess
- Pregnant or lactating females
- Patients with inflamed gingiva or gingival enlargement
- Inflammation or infection at the injection site
- Known allergy to components of Botulinum toxin A or B
- Use of anticholinesterase or agents affecting neuromuscular transmission
- Psychologically unstable individuals or those with unrealistic expectations
- Dependence on facial movements for livelihood (e.g., actors, singers)
- Neuromuscular disorders such as myasthenia gravis or Eaton-Lambert syndrome
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Faculty of Dentistry Cairo University
Cairo, Egypt
Actively Recruiting
Research Team
M
Mawda M Hussain, Bachelor
CONTACT
N
Nesma F Shemais, lecturer
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
3
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