Actively Recruiting

Phase Not Applicable
Age: 10Years - 15Years
All Genders
NCT07424703

Effect of Bright Light Therapy on Idiopathic Scoliosis

Led by Second Affiliated Hospital of Wenzhou Medical University · Updated on 2026-02-20

120

Participants Needed

1

Research Sites

156 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This trial aims to investigate whether morning bright light therapy can reduce the progression rate of idiopathic scoliosis in children and potentially prevent its de novo development.

CONDITIONS

Official Title

Effect of Bright Light Therapy on Idiopathic Scoliosis

Who Can Participate

Age: 10Years - 15Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 10 and 15 years
  • Classified as evening chronotype based on the reduced Horne-6stberg Morningness-Eveningness Questionnaire with score less than 12
  • Underwent standing full-spine X-ray to evaluate idiopathic scoliosis at initial visit
  • Skeletally immature with Risser sign 0-3 and major Cobb angle less than 40 degrees at baseline
  • Provided written informed consent or assent with legal guardian
  • Willing and able to follow the study protocol including device use and follow-up visits
Not Eligible

You will not qualify if you...

  • Plans to move outside the study area within 24 months
  • Used medications affecting circadian rhythm in past 3 months (e.g., lithium, melatonin, melatonergic antidepressants)
  • Traveled across two or more time zones in past 3 months or plans to during study
  • Has eye diseases like glaucoma, retinal disease, or macular degeneration that could interfere with light therapy
  • Diagnosed sleep disorders or medical conditions affecting sleep quality (e.g., narcolepsy, restless legs syndrome, moderate-to-severe eczema)
  • Severe chronic health conditions including syndromic, neuromuscular, or congenital scoliosis causes, past spine surgery or trauma, spinal tumor, leg length difference over 20 mm, poorly controlled diabetes, chronic liver or kidney disease, malabsorption syndromes, or severe obesity with BMI z-score 3 or higher

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

The Second Affiliated Hospital of Wenzhou Medical University

Zhejiang, Zhejiang, China, 325000

Actively Recruiting

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Research Team

X

Xiangyang Wang

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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