Actively Recruiting
Led by Riphah International University · Updated on 2025-11-25
40
Participants Needed
1
Research Sites
1 weeks
Total Duration
This research aims to compare the effects of Bubble Positive Expiratory Pressure (PEP) combined with Segmental Breathing against Incentive Spirometry in children aged 5 to 16 with pleural effusion. Pleural effusion involves excess fluid in the lung cavity, limiting lung expansion and causing breathing difficulties. The study is a randomized clinical trial including 40 pediatric participants to evaluate if Bubble PEP with Segmental Breathing offers a cost-effective alternative to Incentive Spirometry, especially for patients unable to afford mechanical devices. Participants will be randomly assigned to one of two groups. The experimental group will use Bubble PEP therapy and Segmental Breathing along with conventional chest physiotherapy and mobility training daily for two weeks. Bubble PEP involves exhaling through a water-filled bottle to create resistance, while Segmental Breathing focuses on localized lung expansion with therapist guidance. The control group will use Incentive Spirometry combined with chest physiotherapy and mobility training, performing specific breathing exercises and chest percussion. Both groups follow progressive exercise schedules and mobility training over the 14-day intervention. Throughout the study, lung expansion will be measured using X-rays, and breathing difficulty will be assessed with the Pediatric Dyspnea Scale before and after the treatment period. Additional monitoring includes measuring chest expansion, oxygen saturation, and respiratory rate at the start and end of the study. Researchers will analyze these outcomes to understand the effects of each intervention on lung function and breathing in children with pleural effusion. The total participation lasts for two weeks of daily therapy sessions with pre- and post-intervention assessments.
CONDITIONS
Effect of Bubble Positive Expiratory Pressure and Segmental Breathing Versus Incentive Spirometry in Pleural Effusion
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 2 weeks
Participants receive daily therapy sessions using either Bubble Positive Expiratory Pressure combined with Segmental Breathing or Incentive Spirometry, along with conventional chest physiotherapy and mobility training, to improve lung expansion and reduce dyspnea.
Daily sessions for 14 days
Duration - Immediately pre- and post-treatment (within 2 weeks)
Participants undergo assessments of lung expansion, dyspnea, chest expansion, oxygen saturation, and respiratory rate before and after the treatment period to evaluate the effectiveness of the interventions.
2 visits (pre- and post-intervention assessments)
Total: 1 location
1
The Children Hospital and University of Child Health Sciences
Lahore, Punjab Province, Pakistan, 54000
Actively Recruiting
I
IMRAN AMJAD, PhD
M
Muhammad Asif Javed, MS-PT
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
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Elinaldo da Conceição Dos Santos, Juliana de Souza da Silva, Marcus Titus Trindade de Assis Filho...
https://pubmed.ncbi.nlm.nih.gov/31843426