Actively Recruiting
Effect of Calcium-Based Bioceramic Sealer and Resin-Based Sealer on Postoperative Pain
Led by Fatima Memorial Hospital · Updated on 2025-12-24
60
Participants Needed
1
Research Sites
12 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study aims to compare the effect of calcium-based bioceramic sealer and resin-based sealer on postoperative pain in adult patients with asymptomatic apical periodontitis undergoing root canal treatment. Asymptomatic apical periodontitis is a condition where the tissue around the tip of the tooth root is inflamed or shows a lesion on X-ray, but the patient does not experience pain. A total of 60 patients will be randomly assigned to receive root canal treatment with either the bioceramic sealer (Group A) or the resin-based sealer (Group B). Pain after treatment will be measured using a 0-10 Numeric Pain Rating Scale at 4, 24, and 48 hours post-treatment. The highest pain score reported will determine whether the treatment is considered a success (no or mild/moderate pain) or failure (severe pain). The results of this study will provide evidence on which sealer is associated with less postoperative pain, helping clinicians make informed decisions about root canal filling materials.
CONDITIONS
Official Title
Effect of Calcium-Based Bioceramic Sealer and Resin-Based Sealer on Postoperative Pain
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 to 55 years
- Both genders
- Teeth diagnosed with asymptomatic apical periodontitis
- Teeth are asymptomatic with no pain on percussion or palpation
- Non-vital pulp with no response on Electric Pulp Testing
- Teeth with fully formed apices
- Teeth with Periapical Index (PAI) scores 2 to 4 on radiographs
You will not qualify if you...
- Medically compromised patients, including those with immunosuppressive or systemic diseases or on medications affecting healing
- Patients who refuse to participate or cannot communicate symptoms due to psychological disorders
- Teeth where full working length cannot be reached
- Periodontally compromised teeth with probing depth greater than 4 mm
- Complications during treatment such as separation of a file or ledging
- Teeth with overfilling beyond the radiographic apex or short filling more than 2 mm from the radiographic apex
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Fatima Memorial Hospital
Lahore, Punjab Province, Pakistan, 54000
Actively Recruiting
Research Team
S
Shehryar Khan, Bachelor Of Dental SURGERY
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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