Actively Recruiting
Effect of Captopril on GLS in Duchenne Myodystrophy
Led by Ain Shams University · Updated on 2024-07-16
20
Participants Needed
1
Research Sites
39 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
To outline the intermediate term effect of prescribing Captopril as an add on therapy on Left ventricular functions as measured by Global longitudinal strain in patients with Duchenne myodystrophy (DMD)
CONDITIONS
Official Title
Effect of Captopril on GLS in Duchenne Myodystrophy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male patients genetically confirmed with Duchenne myodystrophy (DMD)
- Abnormal global longitudinal strain less than -18%
- At least 6 years old
You will not qualify if you...
- Refusal to sign informed consent
- Contraindications to ACE inhibitors including hypersensitivity, renal impairment, bilateral renal artery stenosis, aortic valve stenosis, hyperkalemia, or hypotension
- Reduced heart ejection fraction below 50%
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Ain Shams university
Cairo, Egypt
Actively Recruiting
Research Team
F
Fatma Ebeid, MD
CONTACT
S
Sandra M Mina
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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