Actively Recruiting

Age: 18Years - 100Years
All Genders
NCT06866431

Effect Of Cavitation In Post-Extractive Socket Healing

Led by International Piezosurgery Academy · Updated on 2025-05-28

84

Participants Needed

1

Research Sites

52 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

In everyday clinical practice, the proper management of the post-extraction socket is crucial in order to enable an optimal healing of the wound and a close post-surgical monitoring is critical to prevent possible complications. After an injury, the cellular reaction starts early, presenting significant changes as soon as 12 to 24 hours later. Favourable wound healing begins with the timely formation, organization, stabilization, and attachment of the blood clot. The stability of the clot is influenced by various factors including the host response, local anatomical characteristics, presence of bacteria and severity of surgical trauma. Delayed healing can lead to increased complications, patient discomfort, and potential procedure failures. In the light of these considerations, the proven effectiveness of piezoelectric devices to facilitate healing mechanisms is known in literature. Inverse piezoelectric effect, as used in current devices, creates mechanical shock waves that oscillate linearly at sonic and ultrasonic frequencies (from 30 to 30.000 Hz). In addition, mechanical micro-movements with a frequency between approximately 24 and 30 kHz create a cavitation effect in the irrigation solution, limiting intraoperative bleeding, thereby increasing the visibility and safety of the procedure. The purpose of the present study is to evaluate if the application of cavitation effect of post-extractive socket is capable of reducing healing time and Numeric Pain Rating Scale (NPRS) values.

CONDITIONS

Official Title

Effect Of Cavitation In Post-Extractive Socket Healing

Who Can Participate

Age: 18Years - 100Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 18 and 100 years
  • Two single rooted hopeless teeth of the same arch to be extracted
  • ASA scale value equal or less than 3
  • Signed informed consent
Not Eligible

You will not qualify if you...

  • General contraindications for dental and/or surgical treatments
  • Inflammatory and autoimmune disease of the oral cavity
  • Uncontrolled diabetes (HbA1c > 7.5%)
  • History of malignancy requiring chemotherapy or radiotherapy within the past five years
  • Previous immunosuppressant bisphosphonate or high dose corticosteroid therapy
  • Heavy smokers (> 20 cigarettes /day)
  • Pregnancy or lactating women
  • No compliance
  • Extraction performed after raising a flap and/or with osteotomy

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

University of Trieste

Trieste, TS, Italy, 34127

Actively Recruiting

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Research Team

C

Claudio Stacchi, Dott.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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