Actively Recruiting
Effect of Cavitation Using Piezoelectric Device on Healing of Post-Extraction Sockets
Led by International Piezosurgery Academy · Updated on 2025-05-28
84
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Proper management of the area after tooth extraction is essential for good healing and to prevent complications. Healing begins quickly after injury, with the formation and stabilization of a blood clot being key for recovery. This study is evaluating whether using ultrasonic cavitation, generated by a piezoelectric device, can reduce healing time and pain after tooth extraction. Participants will undergo extraction of two similar single-rooted teeth on opposite sides of the same jaw. After extraction and cleaning the sockets, one side will receive 90 seconds of ultrasonic cavitation treatment using a special insert with saline solution, while the other side will receive only saline irrigation. Both sites will then be closed with an "X" suture. Patients will be given pain medication instructions and will complete daily pain ratings for 7 days. Follow-up visits will occur on days 3, 7, 14, and 21 to assess healing using a modified Healing Index that scores tissue color, consistency, suppuration, and bleeding. Researchers will analyze tissue quality and pain scores over this period. Data will be collected anonymously and statistically compared to understand the effects of the cavitation treatment on socket healing.
CONDITIONS
Brief Title
Effect Of Cavitation In Post-Extractive Socket Healing
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age between 18 and 100 years
- Two single rooted hopeless teeth of the same arch to be extracted
- ASA scale value equal or less than 3
- Signed informed consent
You will not qualify if you...
- General contraindications for dental and/or surgical treatments
- Inflammatory and autoimmune disease of the oral cavity
- Uncontrolled diabetes (HbA1c > 7.5%)
- History of malignancy requiring chemotherapy or radiotherapy within the past five years
- Previous immunosuppressant bisphosphonate or high dose corticosteroid therapy
- Heavy smokers (> 20 cigarettes /day)
- Pregnancy or lactating women
- No compliance
- Extraction performed after raising a flap and/or with osteotomy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 screening and enrollment visit (in-person)
Duration - 1 day
Participants undergo flapless extraction of two contralateral single-rooted teeth, followed by socket debridement. One site receives ultrasonic cavitation treatment with saline solution, and the other site receives simple saline irrigation. Sutures are applied, and participants receive instructions for post-extraction care.
1 visit (in-person) on the day of extraction
Duration - 21 days
Participants complete a daily pain questionnaire for 7 days and attend follow-up visits for suture removal and tissue healing evaluation. Tissue maturation and quality are assessed at days 3, 7, 14, and 21 after extraction using a modified Healing Index.
Follow-up visits on day 3, day 7 (suture removal), day 14, and day 21 (final check)
Trial Site Locations
Total: 1 location
1
University of Trieste
Trieste, TS, Italy, 34127
Actively Recruiting
Research Team
C
Claudio Stacchi, Dott.
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
Frequently Asked Questions
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