The Effect of Chitin and Ascorbic Acid on Dietary Iron Absorption From Tenebrio Molitor Larvae in Young Women

What this Trial Is About

Iron plays a crucial role in many body functions, including oxygen transport, DNA repair, and muscle metabolism. Iron deficiency, especially among women of childbearing age, adolescents, and young children, is a widespread concern caused by factors like low dietary intake and poor absorption. This trial investigates how chitin, a natural component found in insects, affects iron absorption from insect-based foods and how adding ascorbic acid influences this process. The study uses stable iron isotopes to measure iron absorption specifically from Tenebrio molitor larvae. Participants will consume vegetable soups prepared with different meals containing labeled T. molitor larvae or iron sulfate, with variations including added chitin and ascorbic acid. Seven meal types are tested, each differing in chitin content or ascorbic acid presence to evaluate their impact on iron absorption. The study follows a randomized design with single masking, comparing these meals to understand how chitin and ascorbic acid affect iron uptake. During the study, iron absorption is measured at multiple points: screening, day 16, day 32, and day 47. Researchers will also monitor blood markers such as hemoglobin, serum ferritin, transferrin receptor levels, and inflammation indicators through blood samples taken at the same intervals. The total participation duration is approximately 47 days, during which participants will undergo dietary interventions and regular laboratory assessments to evaluate iron status and absorption.

Effect of Chitin and Ascorbic Acid on Dietary Insect Iron Absorption