Actively Recruiting
Effect of Circadian Rhythm and Physical Exercise in Overweight Type 1 Diabetes Patients
Led by Karolinska Institutet · Updated on 2024-10-15
50
Participants Needed
1
Research Sites
232 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Cardiometabolic risk in patients with abdominal obesity and type 1 diabetes can be moderated by life style modifications. There is an intimate link between gene regulation and circadian rhythm in mediating response to exercise in a variety of insulin sensitive organs. The aim of this project is to evaluate, by intervention, the interplay of circadian rhythm and high intensity interval training (HIIT) on glucose control and skeletal muscle metabolism in patients with overweight with or without type 1 diabetes (T1D).
CONDITIONS
Official Title
Effect of Circadian Rhythm and Physical Exercise in Overweight Type 1 Diabetes Patients
Who Can Participate
Eligibility Criteria
You may qualify if you...
- BMI 25-30
- Type 1 diabetes or healthy subjects
- Age between 18 and 50 years
You will not qualify if you...
- Nicotine usage
- Cardiovascular disease (CVD)
- Blood pressure above 160/95
- Pregnancy
- Treatment with drugs other than insulin, stable thyroid hormone, statins, or antihypertensive drugs (excluding beta blockers)
- Diabetes duration less than 6 months (for diabetes subjects)
- Proliferative or severe non-proliferative retinopathy (for diabetes subjects)
- Chronic kidney disease with GFR below 60 ml/min (for diabetes subjects)
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Ersta sjukhus
Stockholm, Sweden, 11691
Actively Recruiting
Research Team
E
Eva Toft, Assoc Prof
CONTACT
V
Veronica Qvisth, M.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
2
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