Actively Recruiting
Effect of Collagen Membranes on Distal Periodontal Healing of Second Molars After Impacted Mandibular Third Molar Surgery.
Led by University of Medicine and Pharmacy at Ho Chi Minh City · Updated on 2025-08-11
20
Participants Needed
1
Research Sites
121 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Impacted mandibular third molars can cause various complications to the adjacent second molars, such as dental caries, periodontitis, or root resorption. These complications often progress silently and asymptomatically. A typical scenario involves a mesioangularly impacted third molar exerting pressure on the distal alveolar bone of the second molar, resulting in persistent food impaction that is difficult for patients to clean. Furthermore, the surgical removal of deeply impacted or severely angulated mandibular third molars often requires bone removal in the area adjacent to the second molar. These factors may exacerbate distal periodontal defects of the second molar, especially in individuals over the age of 25. This research focuses on evaluating the effectiveness of a new-generation collagen membrane in promoting healing after the extraction of impacted mandibular third molars in patients at risk of distal periodontal tissue damage to the second molars
CONDITIONS
Official Title
Effect of Collagen Membranes on Distal Periodontal Healing of Second Molars After Impacted Mandibular Third Molar Surgery.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged 25 years or older.
- Patients with mesioangular or horizontally impacted mandibular third molars whose highest point is below the occlusal surface of adjacent second molars (classified B, C by Pell - Gregory).
- Patients with symmetrical lower third molars on both sides with the same Pell - Gregory classification and less than 15° difference in inclination.
- Patients with lower second molars on both sides free of cavities or fillings affecting the cemento-enamel junction measurement.
- Patients who have been clearly informed about the study and have signed consent.
You will not qualify if you...
- Patients with coagulation or immune disorders.
- Patients allergic to local anesthetics (Lidocaine 2% with Adrenaline 1:100,000) or drugs used in the study.
- Patients allergic to pig-derived products or food.
- Pregnant or breastfeeding patients.
- Patients who smoke.
- Patients with systemic conditions that prevent surgery.
- Patients showing clinical or radiographic signs of tumors near the mandibular third molar.
- Patients missing mandibular second molars.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University of Medicine and Pharmacy at Ho Chi Minh city
Ho Chi Minh City, Vietnam
Actively Recruiting
Research Team
P
Phong Cu Lam, MD.DDS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
TREATMENT
Number of Arms
2
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