Actively Recruiting
The Effect of Collagen Scaffold Augmentation in Achilles Tendon Rupture Repair
Led by Chinese University of Hong Kong · Updated on 2026-03-25
48
Participants Needed
1
Research Sites
105 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This prospective multicenter randomized controlled trial evaluates the clinical efficacy of collagen scaffold augmentation in surgical repair for acute Achilles tendon ruptures. The study will enroll 48 adult participants randomly assigned to either the intervention group (surgical repair with collagen scaffold augmentation) or the control group (standard surgical repair without scaffold). The primary outcome is tendon function assessed using the VISA-A score, while secondary outcomes include tendon healing characteristics measured by ultrasound (thickness, neovascularity), calf muscle strength, ankle range of motion, and complication rates. Follow-up assessments will be conducted at 6 weeks, 3 months, 6 months, and 12 months post-surgery. The study aims to determine whether collagen scaffold augmentation enhances tendon healing and functional recovery compared to conventional repair methods, potentially offering a improved treatment approach for Achilles tendon injuries.
CONDITIONS
Official Title
The Effect of Collagen Scaffold Augmentation in Achilles Tendon Rupture Repair
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of Achilles tendon rupture
- Age over 18 years
- Able to provide written informed consent
You will not qualify if you...
- Allergy to bovine-derived materials
- Foot or ankle surgery or treatment within the past year
- Ongoing legal case related to current injury
- Active psychological or physical conditions preventing participation, including psychosis, intellectual disability, or stroke
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Prince of Wales Hospital
Shatin, New Territories, Hong Kong, 000000
Actively Recruiting
Research Team
S
Samuel K Ling, MBChB (CUHK), ChM (Edin), MRCS
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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