Study of Probiotics Combined With Vitamin D to Reduce Allergic Rhinitis Symptoms and Improve Quality of Life in Adults

What this Trial Is About

Researchers are evaluating whether taking probiotics, vitamin D, or both together can help reduce symptoms and improve quality of life for adults with allergic rhinitis AR, a condition causing sneezing, nasal congestion, and itchy or watery eyes. This randomized, controlled study includes adults with moderate to severe AR who may have vitamin D insufficiency or deficiency. The goal is to understand if adding these supplements to standard treatment improves symptom severity and quality of life. Participants will be randomly assigned to either standard care alone or standard care plus a combination of vitamin D and probiotics. Those in the combination group will take a daily probiotic capsule and vitamin D tablet for 12 weeks, alongside their usual AR treatments such as antihistamines or nasal sprays. The study aims to assess the combined effect of these supplements on immune markers and symptom relief. During the study, participants will visit the clinic for checkups and lab tests including measurements of nasal symptoms, quality of life surveys, and blood tests for immune markers like IgE and interleukin-13. Researchers will monitor changes from the start of the study through week 12. The findings may provide insight into accessible ways to support management of allergic rhinitis. Participation lasts for 12 weeks of supplementation and observation.

Effect of Combined Probiotics and Vitamin D on Symptoms of Allergic Rhinitis