Actively Recruiting

Phase Not Applicable
Age: 50Years - 85Years
All Genders
NCT06838013

Effect of Combining Central and Peripheral Cutaneous Electrical Stimulation on Lower Limb Motor Function in People With Stroke

Led by The Hong Kong Polytechnic University · Updated on 2025-07-09

92

Participants Needed

1

Research Sites

115 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This study aims to evaluate the effectiveness of transcranial direct current stimulation (tDCS) and transcutaneous electrical nerve stimulation (TENS) in augmenting the efficacy of the lower limb task-oriented training in people with stroke. It is hypothesize that lower limb motor function can be best improved by combining anodal tDCS with TENS, when compared with sham-tDCS with TENS, anodal tDCS with placebo-TENS, or control training at improving ankle muscle strength, motor control of lower limbs, walking performance, functional mobility and community integration in people with stroke.

CONDITIONS

Official Title

Effect of Combining Central and Peripheral Cutaneous Electrical Stimulation on Lower Limb Motor Function in People With Stroke

Who Can Participate

Age: 50Years - 85Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Are between 50 and 85 years of age
  • Have had a single stroke more than 6 months and less than 15 years ago
  • Have at least 5 degrees of active ankle dorsiflexion in the antigravity position
  • Are able to walk 10 meters independently, with or without a walking aid
  • Are able to score 6 or higher out of 10 on the abbreviated mental test
  • Have no skin allergies (such as redness or itchiness) from electrical stimulation or electrodes
  • Are able to follow instructions and give informed consent
Not Eligible

You will not qualify if you...

  • Have any other medical, cardiovascular, or orthopedic conditions that would interfere with treatment or assessment
  • Have a cardiac pacemaker
  • Have aphasia or cognitive difficulties that affect understanding instructions
  • Have had epileptic seizures within the last year
  • Have an intracerebral metal clip
  • Have a major somatosensory deficit
  • Have any contraindications to transcranial direct current stimulation (tDCS)
  • Are currently participating in drug studies or other clinical trials

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

The Hong Kong Polytechnic University

Hong Kong, Hong Kong

Actively Recruiting

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Research Team

S

Shamay NG, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

4

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